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F5180 Sigma

Anti-Fibroblast Growth Factor-Basic antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-BFGF, Anti-FGF2, Anti-FGFB, Anti-HBGF-2

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cytokines and Growth Factors, Antibodies to Fibroblast Growth Factors (FGF),
species reactivity   human, bovine
application(s)   immunohistochemistry: 5-15 μg/mL
  neutralization: suitable
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   bovine ... FGF2(281161)
human ... FGF2(2247)
biological source   goat
conjugate   unconjugated
Featured Industry   Research Pathology

Description

Immunogen

purified bovine fibroblast growth factor basic peptide (146 aa).

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Features and Benefits

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Biochem/physiol Actions

Fibroblast Growth Factor Basic (also known as bFGF) is a pleotropic cytokine that that is a potent mitogenic factor. On binding to its cognate receptor tyrosine kinase, FGFR, bFGF is capable of activation of pathways such as MAPK and PI3K and produce cellular effects in varied cell types. Fibroblast Growth Factor-basic is reported to induce proliferation of fibroblasts, differentiation, wound healing and regeneration, limb formation, tissue remodeling and angiogenesis.

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Safety & Documentation

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  1
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

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F5305 Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse, clone 10060, purified immunoglobulin, lyophilized powder
F6162 Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse, clone FB-8, purified immunoglobulin, buffered aqueous solution
F0291 hBFGF, FGF-Basic, recombinant, expressed in E. coli, suitable for cell culture
F5392 Fibroblast Growth Factor-Basic from bovine pituitary, FGF-Basic, suitable for cell culture
F5537 Anti-Fibroblast Growth Factor-Basic antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution
F3393 Anti-Fibroblast Growth Factor-Basic (1-24) antibody produced in rabbit, fractionated antiserum, lyophilized powder
F9786 Fibroblast Growth Factor-Basic Heparin Stabilized human, FGF-Basic, recombinant, expressed in E. coli, sterile-filtered, aqueous solution, suitable for cell culture

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