• USA Home
  • F5305 - Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse

EMAIL THIS PAGE TO A FRIEND
F5305 Sigma

Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse

clone 10060, purified immunoglobulin, lyophilized powder

Synonym: Anti-FGF2

Purchase

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cytokines and Growth Factors, Antibodies to Fibroblast Growth Factors (FGF),
species reactivity   human
application(s)   capture ELISA: 2-8 μg/mL
clone   10060, monoclonal
antibody form   purified immunoglobulin
form   lyophilized powder
isotype   IgG2a
storage temp.   −20°C
Gene Information   human ... FGF2(2247)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

purified, E. coli-derived recombinant human fibroblast growth factor basic.

General description

Fibroblast Growth Factor Basic (also known as bFGF) is a pleotropic cytokine that that is a potent mitogenic factor. On binding to its cognate receptor tyrosine kinase, FGFR, bFGF is capable of activation of pathways such as MAPK and PI3K and produce cellular effects in varied cell types. Fibroblast Growth Factor-basic is repoted to induce proliferation of fibroblasts, differentiation, wound healing and regeneration, limb formation, tissue remodelling and angiogenesis. The role of bFGF in chondrocyte proliferation and repair has established the role of bFGF in maintaining cartilage and intervertebral disc homeostasis. Along with VEGF, bFGF is important in angiogenesis and tumorigenesis in response to inflammatory cytokines
Monoclonal Anti-Fibroblast Growth Factor Basic recognizes human Fibroblast Growth Factor Basic. It also recognizes bovine bFGF. It shows 0.2% cross-reactivity with bovine FGF acidic. It does not react with human FGF acidic, FGF-4, -6 or -7.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Application

Monoclonal Anti-Fibroblast Growth Factor Basic may be used as capture antibody in ELISA at a recommended concentration range of 2-8 μg/ml.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Price and Availability


Antibody Explorer

Explore with Confidence
Safety & Documentation

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  1
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

F5180 Anti-Fibroblast Growth Factor-Basic antibody produced in goat, affinity isolated antibody, lyophilized powder
F6162 Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse, clone FB-8, purified immunoglobulin, buffered aqueous solution
F0291 hBFGF, FGF-Basic, recombinant, expressed in E. coli, suitable for cell culture
F5392 Fibroblast Growth Factor-Basic from bovine pituitary, FGF-Basic, suitable for cell culture
F5537 Anti-Fibroblast Growth Factor-Basic antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution
F3393 Anti-Fibroblast Growth Factor-Basic (1-24) antibody produced in rabbit, fractionated antiserum, lyophilized powder
F9786 Fibroblast Growth Factor-Basic Heparin Stabilized human, FGF-Basic, recombinant, expressed in E. coli, sterile-filtered, aqueous solution, suitable for cell culture

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?