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F5631 Sigma

Fucoidan from Fucus vesiculosus

Crude

Synonym: Fucoidin

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Properties

Related Categories Carbohydrates, Cell Biology, Functional Foods, Nutrition Research, Polysaccharide More...
quality   Crude
solubility   H2O: soluble10 mg/mL, clear to hazy, faintly yellow to brownish-yellow

Description

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Frequently Asked Questions are available for this Product.

General description

Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.

Packaging

1 g in poly bottle

500 mg in poly bottle

Preparation Note

Prepared by a modification of the method of Black, W.A.P., et al., J. Sci. Food Agri., 3, 122 (1952).

Application

Fucoidan from Fucus vesiculosus may be used as a biological response modifier and as a potential therapeutic agent with a wide range of biological activities. It may be used to study its pharmacokinetics, safety, efficacy and methods of delivery as a potential anticancer, anti-immune and anti-inflammatory agent. Fucoidan may be used to assess its potential and formulations for tissue engineering applications.

Biochem/physiol Actions

Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation with subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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