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F5682 Sigma

FH535

≥98% (HPLC)

  • Empirical Formula (Hill Notation) C13H10Cl2N2O4S

  • Molecular Weight 361.20

  •  MDL number MFCD01212888

  •  PubChem Substance ID 329799746

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, F,
InChI Key   AXNUEXXEQGQWPA-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
solubility   DMSO: soluble20 mg/mL
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

FH535 is a reversible dual inhibitor of Wnt/β-catenin and a PPARγ and PPARδ signaling antagonist. FH535 is unique in its ability to inhibit the Wnt/β-catenin pathway. The compound is selectively toxic to some carcinomas expressing the Wnt/β-catenin pathway.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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