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F5881 Sigma

Freund’s Adjuvant, Complete

cell suspension

Synonym: FCA

Properties

Related Categories Adjuvant emulsions, Adjuvants, Antibodies, Antibody Purification and Characterization, Cell Culture,
form   cell suspension
color   amber
storage temp.   2-8°C

Description

Frequently Asked Questions

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General description

Each mL contains 1 mg of Mycobacterium tuberculosis (H37Ra, ATCC 25177), heat killed and dried, 0.85 mL paraffin oil and 0.15 mL mannide monooleate.

Application

Antigens (preferably in saline) are typically mixed with an equal volume of the adjuvant to form an emulsion.1

Freund′s Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions stimulate high and long-lasting antibody responses which can be attributed to the slow release of antigen.

Biochem/physiol Actions

The mycobacteria in Complete Freund′s adjuvant attracts macrophages and other cells to the injection site which enhances the immune response. For this reason, Complete Freund′s Adjuvant is used for initial injections and Incomplete Freund′s Adjuvant for subsequent boosts.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.




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