|Related Categories||Adjuvant emulsions, Adjuvants, Antibodies, Antibody Purification and Characterization, Cell Culture,|
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Each mL contains 1 mg of Mycobacterium tuberculosis (H37Ra, ATCC 25177), heat killed and dried, 0.85 mL paraffin oil and 0.15 mL mannide monooleate.
Freund′s Adjuvants may be used to produce water-in-oil emulsions of immunogens. Antigens in water-in-oil emulsions stimulate high and long-lasting antibody responses which can be attributed to the slow release of antigen.
The mycobacteria in Complete Freund′s adjuvant attracts macrophages and other cells to the injection site which enhances the immune response. For this reason, Complete Freund′s Adjuvant is used for initial injections and Incomplete Freund′s Adjuvant for subsequent boosts.
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In vivo molecular imaging of experimental joint inflammation by combined (18)F-FDG positron emission tomography and computed tomography. Irmler IM, Opfermann T, Gebhardt P, et al. Arthritis. Res. Ther. 12(6), R203, (2010)
Antigenic analysis of classical swine fever virus E2 glycoprotein using pig antibodies identifies residues contributing to antigenic variation of the vaccine C-strain and group 2 strains circulating in China. Chen N, Tong C, Li D, et al. Virol. J. 7, 378, (2010)
Biological and immunological characterization of recombinant Yellow Fever 17D viruses expressing a Trypanosoma cruzi Amastigote Surface Protein-2 CD8+ T cell epitope at two distinct regions of the genome. Nogueira RT Virol. J. 8, 127, (2011)
Nanovaccine for leishmaniasis: preparation of chitosan nanoparticles containing Leishmania superoxide dismutase and evaluation of its immunogenicity in BALB/c mice. Danesh-Bahreini MA, Shokri J, Samiei A, et al. Int. J. Nanomedicine 6, 835-42, (2011)
Genetic evidence for an essential role of neuronally expressed IL-6 signal transducer gp130 in the induction and maintenance of experimentally induced mechanical hypersensitivity in vivo and in vitro. Quarta S, Vogl C, Constantin CE, et al. Mol. Pain 7, 73, (2011)
Mineral-oil Adjuvants and the Immunization of Laboratory Animals. Herbert, W.J., Weir, D.M. Handbook of Experimental Immunology Oxford , (1978)
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