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F5900 Sigma

Monoclonal Anti-Interleukin-2−Carboxyfluorescein antibody produced in mouse

clone 5334, purified immunoglobulin, buffered aqueous solution

Synonym: Monoclonal Anti-IL-2, Monoclonal Anti-Interleukin-2

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Description

Immunogen

recombinant human IL-2

General description

Interleukin-2 (IL-2) also refers as T Cell Growth Factor is a cytokine produced by certain subsets of T lymphocytes. It plays various functions like inducing interferon γ and B cell growth factor secretion as well as affecting the activation and proliferation of NK cells. It also has a vital role in modulating the expression of the IL-2 receptor and can facilitate B cell growth and differentiation. Monoclonal anti-Interleukin-2−Carboxyfluorescein antibody reacts specifically with human IL-2.

Physical form

Solution in phosphate buffered saline containing 0.1% sodium azide.

Specificity

The conjugates will identify and quantitate cells containing intracellular forms of human IL-2 by flow cytometry.

Preparation Note

Purified antibody is conjugated to carboxyfluorescein.

Application

Monoclonal anti-Interleukin-2−Carboxyfluorescein antibody can be used in flow cytometry assays for identifying intracytoplasmic cytokines and for enumerating cytokine producing cells present in a mixed population.

Features and Benefits

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Safety & Documentation

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

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Peer-Reviewed Papers
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References

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