• USA Home
  • F6162 - Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse

EMAIL THIS PAGE TO A FRIEND
F6162 Sigma

Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse

clone FB-8, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-FGF2

Purchase

Properties

Related Categories Alphabetical Index, Angiogenesis, Antibodies, Antibodies for Cell Biology, Antibodies for Hematopoietic Stem Cells,
species reactivity   human, bovine
application(s)   dot blot: suitable
  indirect ELISA: suitable
  neutralization: 5 μg/mL using 1 unit recombinant human FGF2 in mouse 3T3 cells
  radioimmunoassay: suitable
  western blot: suitable
clone   FB-8, monoclonal
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
mol wt   antigen mol wt 18 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... FGF2(2247)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

recombinant human FGF2.

General description

The antibody reacts specifically with both native and recombinant human FGF2. It does not cross-react with human FGF1.

Physical form

Solution, 0.2 μm filtered, in phosphate buffered saline, pH 7.4.

Application

Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse was used in protein pin array assay to identify the interactive sequences in human αB crystalline protein. The antibody can be used for neutralization of the biological activity of FGF2 in cell culture.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

Fibroblast Growth Factor Basic (also known as bFGF) is a pleotropic cytokine that that is a potent mitogenic factor. On binding to its cognate receptor tyrosine kinase, FGFR, bFGF is capable of activating pathways such as MAPK and PI3K and produce cellular effects in varied cell types. Fibroblast Growth Factor-basic is reported to induce proliferation of fibroblasts, differentiation, wound healing and regeneration, limb formation, tissue remodeling and angiogenesis.

Price and Availability


Antibody Explorer

Explore with Confidence

All labs need water
Safety & Documentation

Safety Information

Personal Protective Equipment  Eyeshields, Gloves
RIDADR  NONH for all modes of transport
WGK Germany  3
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

F5180 Anti-Fibroblast Growth Factor-Basic antibody produced in goat, affinity isolated antibody, lyophilized powder
F5305 Monoclonal Anti-Fibroblast Growth Factor-Basic antibody produced in mouse, clone 10060, purified immunoglobulin, lyophilized powder
F0291 hBFGF, FGF-Basic, recombinant, expressed in E. coli, suitable for cell culture
F5392 Fibroblast Growth Factor-Basic from bovine pituitary, FGF-Basic, suitable for cell culture
92210 Timestrip Plus 0 °C
F5537 Anti-Fibroblast Growth Factor-Basic antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution
F3393 Anti-Fibroblast Growth Factor-Basic (1-24) antibody produced in rabbit, fractionated antiserum, lyophilized powder
F9786 Fibroblast Growth Factor-Basic Heparin Stabilized human, FGF-Basic, recombinant, expressed in E. coli, sterile-filtered, aqueous solution, suitable for cell culture

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?