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F6625 Sigma

Flavin adenine dinucleotide disodium salt hydrate

≥95% (HPLC), powder

Synonym: FAD-Na2, FAD, Riboflavin 5′-adenosine diphosphate disodium salt

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cofactors, Cofactors and Substrates, Core Bioreagents,
InChI Key   GXTPHHZYFMAGLX-UJXBNFGUSA-L
assay   ≥95% (HPLC)
form   powder
color   yellow to orange-brown
storage temp.   −20°C

Description

Packaging

1 g in poly bottle

10, 25, 100, 250, 500 mg in poly bottle

Application

Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Mitochondrial Stress and ROS

Oxidative stress is implicated in the pathogenesis of lipotoxicity in both animal and human studies. Chronic oxidative stress is linked to insulin resistance in multiple tissues. Oxidative stress is ...
BioFiles 2011, 6.4, 22.
Keywords: Anti-inflammatory agents, Apoptosis, Cancer, Cell signaling, Cellular processes, Gene expression, Indicators, Metabolism, Oxidations, Respiratory

Pyruvate Transformations

Depending on the environmental conditions, e.g. whether oxygen is present or not, pyruvate, a product of glucose metabolism, can undergo different biotransformations as shown in Figure 2. Under reduc...
BioFiles 2007, 2.6, 10.
Keywords: Anaerobic, Biofiles, Catalysis, Environmental, Metabolism

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