F8129 Sigma

Acid Fuchsin

used in tissue staining

Synonym: Acid Violet 19, Fuchsin S, Fuchsin acid, Rubine S

  • CAS Number 3244-88-0

  • Empirical Formula (Hill Notation) C20H17N3Na2O9S3

  • Molecular Weight 585.54

  •  Beilstein Registry Number 4111656

  •  Colour Index Number 42685

  •  EC Number 221-816-5

  •  PubChem Substance ID 24894958

  • Popular Documents:  Specification Sheet (PDF)  



Related Categories A, Cell Biology, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes More...
form   powder
composition   Dye content, ~70%
solubility   H2O: soluble1 mg/mL



25, 50, 100 g in glass bottle

Price and Availability

Suggested Laboratory Gloves

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certified by the Biological Stain Commission, Dye content ≥88 %

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Van Gieson Solution Acid Fuchsin

for in vitro diagnostic use

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles

Peer-Reviewed Papers


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The sulfated triphenyl methane derivative acid fuchsin is a potent inhibitor of amyloid formation by human islet amyloid polypeptide and protects against the toxic effects of amyloid formation. Meng F, Abedini A, Plesner A, et al. J. Mol. Biol. 400(3), 555-66, (2010)


Ability of 13 chemical agents used in dental practice to induce sister-chromatid exchanges in Syrian hamster embryo cells. Miyachi T and Tsutsui T Odontology 93(1), 24-9, (2005)


Effect of enamel matrix derivative (Emdogain) on bone defects in rabbit tibias. Cornelini R, Scarano A, Piattelli M, et al. J. Oral Implantol. 30(2), 69-73, (2004)


Bone regeneration with calcium sulfate: evidence for increased angiogenesis in rabbits. Strocchi R, Orsini G, Iezzi G, et al. J. Oral Implantol. 28(6), 273-8, (2002)


Bone response to machined and resorbable blast material titanium implants: an experimental study in rabbits. Piattelli M, Scarano A, Paolantonio M, et al. J. Oral Implantol. 28(1), 2-8, (2002)


Histologic evaluation of a human immediately loaded titanium implant with a porous anodized surface. Degidi M, Petrone G, Iezzi G, et al. Clin. Implant Dent. Relat. Res. 4(2), 110-4, (2002)


Immediate implantation in fresh extraction sockets. A controlled clinical and histological study in man. Paolantonio M, Dolci M, Scarano A, et al. J. Periodontol. 72(11), 1560-71, (2001)


Needle-like Zn-doped SnO2 nanorods with enhanced photocatalytic and gas sensing properties. Huang H, Tian S, Xu J, et al. Nanotechnology 23(10), 105502, (2012)


Polyelectrolyte multilayer-assisted immobilization of zero-valent iron nanoparticles onto polymer nanofibers for potential environmental applications. Xiao S, Wu S, Shen M, et al. ACS Appl. Mater. Interfaces 1(12), 2848-55, (2009)


Optimal conditions for visualizing water-conducting pathways in a living tree by the dye injection method. Umebayashi T, Utsumi Y, Koga S, et al. Tree Physiol. 27(7), 993-9, (2007)


Enhanced photocatalytic discoloration of acid fuchsine wastewater by TiO2/schorl composite catalyst. Xu HY, Zheng Z, and Mao GJ J. Hazard. Mater. 175(1-3), 658-65, (2010)


Hard and soft tissue responses to the platform-switching technique. Luongo R, Traini T, Guidone PC, et al. Int. J. Periodontics Restorative Dent. 28(6), 551-7, (2008)


Characterization of conformational changes and noncovalent complexes of myoglobin by electrospray ionization mass spectrometry, circular dichroism and fluorescence spectroscopy. Lin X, Zhao W, and Wang X J. Mass Spectrom. 45(6), 618-26, (2010)


Cytosolic labile zinc: a marker for apoptosis in the developing rat brain. Lee JY, Hwang JJ, Park MH, et al. Eur. J. Neurosci. 23(2), 435-42, (2006)


Basophilia, acidophilia and argyrophilia of "dark" (compacted) neurons during their formation, recovery or death in an otherwise undamaged environment. Zsombok A, Tóth Z, and Gallyas F J. Neurosci. Methods 142(1), 145-52, (2005)


Nonlinear studies of acid fuchsin dye in liquid and solid media. Vinitha G and Ramalingam A Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 69(4), 1160-4, (2008)


Protective effect of ginsenosides, active ingredients of Panax ginseng, on kainic acid-induced neurotoxicity in rat hippocampus. Lee JH, Kim SR, Bae CS, et al. Neurosci. Lett. 325(2), 129-33, (2002)


Inhibition of glycosaminoglycan-mediated amyloid formation by islet amyloid polypeptide and proIAPP processing intermediates. Meng F and Raleigh DP J. Mol. Biol. 406(3), 491-502, (2011)


Degradation of acid fuchsine by a modified electro-Fenton system with magnetic stirring as oxygen supplying. Sheng Y, Zhen L, Wang X, et al. J. Environ. Sci. (China) 22(4), 547-54, (2010)


One-step purification of rabbit histidine rich glycoprotein by dye-ligand affinity chromatography with metal ion requirement. Mori S, Nishibori M, Yamaoka K, et al. Arch. Biochem. Biophys. 383(2), 191-6, (2000)


Multicolor counterstaining for immunohistochemistry -- a modified Movat's pentachrome. Petrovic A, Abramovic M, Mihailovic D, et al. Biotech. Histochem. 86(6), 429-35, (2011)


[Determination of protein concentration by the enhancement of Rayleigh light scattering of fuchsine acid]. Zhang HY, Liu BS, Zhang HL, et al. Guang Pu Xue Yu Guang Pu Fen Xi 22(6), 1054-6, (2002)


Protective effect of etomidate on kainic acid-induced neurotoxicity in rat hippocampus. Lee J, Kim D, Hong H, et al. Neurosci. Lett. 286(3), 179-82, (2000)


A histochemical comparison of methylene-blue/acid fuchsin with hematoxylin and eosin for differentiating calcification of stromal tissue. Gupta K, Kale AD, Hallikeremath SR, et al. Biotech. Histochem. 87(4), 249-56, (2012)


Differentiation of bone and soft tissues in formalin-fixed, paraffin-embedded tissue by using methylene blue/acid fuchsin stain. Rider KA and Flick LM Anal. Quant. Cytol. Histol. 26(5), 246-8, (2004)


Hydrogen peroxide primes heart regeneration with a derepression mechanism. Han P, Zhou XH, Chang N, et al. Cell Res. 24(9), 1091-107, (2014)


Merck 14,107

Beil. 14,IV,2827

RegBook 1 (2), 2779:N / Stains and Dyes Ref, 21 / Structure Index 1, 442:C:3

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