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F8507 Sigma

(±)-Fenfluramine hydrochloride

Synonym: (±)-N-Ethyl-α-methyl-m-[trifluoromethyl]phenethylamine hydrochloride

  • CAS Number 16105-77-4

  • Empirical Formula (Hill Notation) C12H16F3N · HCl

  • Molecular Weight 267.72

  •  MDL number MFCD00058016

  •  PubChem Substance ID 24894965

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Neurotransmission (Obesity),
InChI Key   ZXKXJHAOUFHNAS-UHFFFAOYSA-N
drug control   USDEA Schedule IV

Description

Biochem/physiol Actions

Neurotoxic on prolonged administration or at high dosage; releases serotonin from axon terminals by a nonexocytotic mechanism; anorectic

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Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
DA0295500

Documents

Certificate of Analysis

Protocols & Articles

Articles

History of Biogenic Amine Use for Treating Obesity

The discovery of ephedrine (Product No. E2750) in the 1930s led to the synthesis of amphetamines. Initially utilized as stimulants, they were soon shown to exhibit food intake and appetite suppressin...
Keywords: Obesity

Peer-Reviewed Papers
15

References

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