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F8527 Sigma

Monoclonal Anti-CD45−FITC/CD14-PE DUAL-TAG antibody produced in mouse

clone BRA-55/UCHM-1, purified immunoglobulin, buffered aqueous solution

Properties

Related Categories Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Cell Biology, Antibodies for Immune Cell Signaling and Blood,
species reactivity   human
application(s)   flow cytometry: 20 μL using 1 × 106 cells
clone   BRA-55/UCHM-1, monoclonal
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1/IgG2a
shipped in   wet ice
storage temp.   2-8°C
Gene Information   human ... CD14(929), PTPRC(5788)
biological source   mouse
conjugate   FITC conjugate
  phycoerythrin (R-PE) conjugate

Description

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.

Application

Monoclonal Anti-CD45-FITC/CD14-PE DUAL-TAG antibody is suitable for flow cytometry at a concentration of 20μL using 1×106 cells.

Legal Information

DUAL-TAG is a trademark of Sigma-Aldrich Co. LLC

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

CD45 is a family of single chain transmembrane glycoproteins, consisting of different isoforms, which share a common large intracellular domain. It is abundantly present in leukocyte cell surface and belongs to a novel class of enzymes, the protein tyrosine phosphatases (PTPs). It plays an essential role in thymic selection and peripheral activation of T and B cells. It is associated with various signal transduction pathways. It may also accelerate the Src family tyrosine kinases activity. an important determinant of immune tolerance.

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