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F9049 Sigma

Anti-Fibroblast Growth Factor-10 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-FGF-10

Description

Immunogen

recombinant human fibroblast growth factor 10 expressed in E. coli.

General description

Fibroblast Growth Factor 10 (FGF-10) is a protein expressed mainly in the embryo and adult lung as well as in adult fibroblasts and pre-adipocytes. It has mitogenic activity for epithelial and epidermal cells but not for fibroblasts. FGF-10 plays a crucial role in lung development, wound healing and limb bud formation. It is also required for normal branching morphogenesis. Anti-Fibroblast Growth Factor-10 antibody can be used in indirect ELISA at a working antibody concentration of 0.5-1.0 μg/ml. Goat anti-Fibroblast Growth Factor-10 antibody reacts specifically with recombinant human FGF-10. The antibody exhibits 30% (approx.) cross-reactivity with recombinant human FGF-7 and 15% with recombinant human FGF-5.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Application

Anti-Fibroblast Growth Factor-10 antibody can be used in western blotting at a working antibody concentration of 0.1-0.2 μg/ml.

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