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  • F9681 - Anti-FCGR2B (271-285) antibody produced in rabbit

F9681 Sigma

Anti-FCGR2B (271-285) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-CD32, Anti-CD32B, Anti-FCG2, Anti-FCGR2, Anti-Fc fragment of IgG, low affinity IIb, receptor for (CD32) isoform 4, Anti-IGFR2



Related Categories Alphabetical Index, Antibodies, FB-FJ, Primary Antibodies
species reactivity   human
application(s)   western blot: 1:500-1:2,000
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
mol wt   antigen mol wt ~34 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... FCGR2B(2213)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 271-285 of human FCGR2B

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Anti-FCGR2B (271-285) antibody is suitable for western blot at a dilution of 1:500-1:2,000.
Yale Center for High Throughput Cell Biology IF-tested antibodies. Each antibody is tested by immunofluorescence against HUVEC cells using the Yale HTCB IF protocol. To learn more about the Sigma Life Science and Yale Center for High Throughput Cell Biology partnership, visit sigma.com/htcb-if.

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Biochem/physiol Actions

FcγRIIB is a type I transmembrane receptor with low affinity for monomeric IgG. It is expressed by B cells and plasma cells. It acts as predominant Fc receptor (FcR) present on B cells. It plays a critical regulatory role in B-cell homeostasis as well as in immune response and inflammatory effects. FcγRIIB regulates the threshold and the extent of cell activation by counter balancing the stimulatory activity of a variety of receptors, including the B-cell antigen receptor.

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