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G013 Sigma

R(+)-Baclofen hydrochloride

solid

Synonym: Arbaclofen hydrochloride, R(+)-β-(Aminomethyl)-4-chlorobenzenepropanoic acid hydrochloride, STX209

  • CAS Number 63701-55-3

  • Empirical Formula (Hill Notation) C10H12ClNO2 · HCl

  • Molecular Weight 250.12

  •  MDL number MFCD00078579

  •  PubChem Substance ID 24895006

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Properties

Related Categories Agonists, Cell Biology, Cell Signaling and Neuroscience, GABAergics, Neuroscience,
InChI Key   WMNUVYYLMCMHLU-QRPNPIFTSA-N
form   solid
optical activity   [α]28/D +3.8°, c = 0.9 in methanol(lit.)
color   white
solubility   DMSO: >20 mg/mL
  H2O: soluble26 mg/mL (Solutions may be stored for several weeks at 4 °C.)
Gene Information   human ... GABBR1(2550)
mouse ... GABBR1(54393)
rat ... GABBR1(81657)

Description

Biochem/physiol Actions

R(+)-Baclofen is a GABAB receptor agonist; more active enantiomer; skeletal muscle relaxant.

Other Notes

Same enantiomer as R(−)-baclofen free base.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
MW5084350

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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