• USA Home
  • G0291 - Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C2) antibody produced in rabbit

EMAIL THIS PAGE TO A FRIEND
G0291 Sigma

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C2) antibody produced in rabbit

affinity isolated antibody, lyophilized powder

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Neurotransmission, Antibodies to Glutamate Receptors,
species reactivity   rat, mouse
application(s)   immunohistochemistry: 1:1,000
  western blot: 1:1,000
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
mol wt   antigen mol wt 100 kDa
storage temp.   2-8°C
Gene Information   mouse ... Grin1(14810)
rat ... Grin1(24408)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide representing the sequence of the C2 splice variant.

Physical form

Lyophilized powder from 5 mM ammonium bicarbonate (some residual salt may be present).

Application

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert C2) antibody is suitable for immunohistochemistry (frozen sections) and western blot at a dilution of 1:1000.

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Biochem/physiol Actions

NMDA receptors (NMDAR) are glutamate-gated ion channels. It is sensitive to N-methyl-D-aspartate (NMDA) and consists of several homologous subunits (NMDAR1). NMDAR is highly expressed in the central nervous system and involved in excitatory synaptic transmission as well as synaptic plasticity. The activity of NMDA receptors are modulated by glycine. It exhibits high calcium permeability and unique voltage-dependent sensitivity to magnesium. It has been reported that phosphorylated NMDA receptors may regulate their function and play a role in many forms of synaptic plasticity such as long-term potentiation.

Price and Availability


Antibody Explorer

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?