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  • G0541 - Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody produced in rabbit

G0541 Sigma

Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody produced in rabbit

affinity isolated antibody, lyophilized powder


Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Neurotransmission, Antibodies to Glutamate Receptors,
species reactivity   rat
application(s)   dot blot: 1:1000
  immunohistochemistry: 1:1000
  western blot: 1:1000
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
mol wt   antigen mol wt 100 kDa
storage temp.   2-8°C
Gene Information   rat ... Grin1(24408)
biological source   rabbit
conjugate   unconjugated



synthetic peptide representing the sequence of the N1 splice variant.

Physical form

Lyophilized powder from 5 mM ammonium bicarbonate (some residual salt may be present)


Anti-Glutamate Receptor NMDAR1 (NR1) (Splice Variant Insert N1) antibody is suitable for dot blot, immunohistochemistry and western blot at a dilution of 1:1000.

Features and Benefits

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Biochem/physiol Actions

NMDA receptors (NMDAR) are glutamate-gated ion channels. It is sensitive to N-methyl-D-aspartate (NMDA) and consists of several homologous subunits (NMDAR1). NMDAR is highly expressed in the central nervous system and involved in excitatory synaptic transmission as well as synaptic plasticity. The activity of NMDA receptors are modulated by glycine. It exhibits high calcium permeability and unique voltage-dependent sensitivity to magnesium. It has been reported that phosphorylated NMDA receptors may regulate their function and play a role in many forms of synaptic plasticity such as long-term potentiation.

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