G0639 Sigma

Glybenclamide

≥99% (HPLC)

DOWNLOAD MSDS (PDF)

Synonym: 5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide, Glyburide, N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N′-cyclohexylurea

Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, G,
assay   ≥99% (HPLC)
solubility   ethanol: soluble2 mg/mL
  DMSO: soluble
  H2O: insoluble
storage temp.   2-8°C
Gene Information   human ... KCNH2(3757), KCNJ1(3758), KCNJ11(3767)
rat ... Kcnj1(24521)

Description

Biochem/physiol Actions

Selectively blocks ATP-sensitive K+ channels; high affinity binding sites found in brain, pancreatic β cells, and cardiovascular system.

Price and Availability

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