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G113 Sigma

GR 64349

>96%

  • CAS Number 137593-52-3

  • Empirical Formula (Hill Notation) C42H68N10O11S

  • Molecular Weight 921.11

  •  PubChem Substance ID 329799740

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Description

Amino Acid Sequence

Lys-Asp-Ser-Phe-Val-Gly-R-γ-lactam-Leu-Met-NH2

Packaging

1 mg in glass bottle

Biochem/physiol Actions

GR 64349 peptide acts as an agonist of neurokinin (NK2) receptor, which leads to reduced NK2 response to kainate and AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), but not to NMDA (N-methyl-D-aspartate).

General description

Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK2 is GR 64349 peptide.

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Amplified Detection

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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