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G119 Sigma

GYKI 52466 hydrochloride

solid

Synonym: 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride

  • CAS Number 192065-56-8

  • Empirical Formula (Hill Notation) C17H15N3O2 · HCl

  • Molecular Weight 329.78

  •  MDL number MFCD00153803

  •  PubChem Substance ID 24277984

Properties

Related Categories AMPA/Kainate Antagonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
assay   ≥98% (HPLC)
form   solid
color   yellow
solubility   DMSO: soluble0.39 mg/mL
  ethanol: soluble0.4 mg/mL
  0.1 M HCl: soluble0.68 mg/mL
  methanol: soluble1 mg/mL
  H2O: >10 mg/mL
Gene Information   human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893)

Description

Biochem/physiol Actions

Selective allosteric AMPA receptor antagonist; anti­convulsant; skeletal muscle relaxant.

Legal Information

Sold under exclusive license from the Institute for Drug Research Ltd., Budapest, Hungary.

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®,1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Price and Availability

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