G119 Sigma

GYKI 52466 hydrochloride


Synonym: 1-(4-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride

  • CAS Number 192065-56-8

  • Empirical Formula (Hill Notation) C17H15N3O2 · HCl

  • Molecular Weight 329.78

  •  MDL number MFCD00153803

  •  PubChem Substance ID 24277984


Related Categories AMPA/Kainate Antagonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids,
assay   ≥98% (HPLC)
form   solid
color   yellow
solubility   DMSO: soluble0.39 mg/mL
  ethanol: soluble0.4 mg/mL
  0.1 M HCl: soluble0.68 mg/mL
  methanol: soluble1 mg/mL
  H2O: >10 mg/mL
Gene Information   human ... GRIA1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893)


Biochem/physiol Actions

Selective allosteric AMPA receptor antagonist; anti­convulsant; skeletal muscle relaxant.

Legal Information

Sold under exclusive license from the Institute for Drug Research Ltd., Budapest, Hungary.

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