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G1290 Sigma

GFRα-3/Fc Chimera human

≥90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, cell culture tested

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, GDNF and Receptors,
recombinant   expressed in baculovirus infected Sf21 cells
assay   ≥90% (SDS-PAGE)
form   lyophilized powder
impurities   endotoxin, tested
suitability   cell culture tested
storage temp.   −20°C
Gene Information   human ... GFRA3(2676)

Description

Physical form

Lyophilized from a 0.2 μm solution in phosphate buffered saline.

Application

GFRα-3/Fc Chimera human has been used for human umbilical vein endothelial cells (HUVECs) proliferation assay and apoptosis assessment.

Biochem/physiol Actions

GFRA3 (GDNF family receptor α3) interacts with artemin (ARTN) protein to form the ternary signaling complex, which contains the shared RET (receptor tyrosine kinase) receptor. The expression of this protein, along with GFRA1 and ARTN, might be useful in determining the prognosis of certain subsets of mammary carcinoma.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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