Synonym: Galantamine hydrobromide
|Related Categories||A to C, Acetylcholinesterase, Analytical and Industrial Enzymes, Bioactive Small Molecules, Biochemicals and Reagents,|
Cholinesterase inhibitor; reverses scopolamine-induced amnesia; antimyasthenic.
Bottomless glass bottle. Contents are inside inserted fused cone.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P301 + P310|
|Personal Protective Equipment||Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||25|
|Safety Statements (Europe)||45|
|RIDADR||UN 2811 6.1 / PGIII|
Acetylcholine is synthesized from acetyl coenzyme A and choline by the enzyme choline acetyltransferase. In the nervous system, this enzyme is thought to exist primarily in the nerve terminal cytopla...
Keywords: Clinical, Enzyme activity, Insecticides, Phosphorylations, Transcription
Galantamine Inhibits Slowly Inactivating K+ Currents With A Dual Dose-response Relationship In Differentiated N1E-115 Cells And In CA1 Neurones. Vicente, M.I., et al. Eur. J. Cancer 634, 16-25, (2010)
Acetylcholinesterase inhibition promotes retinal vasoprotection and increases ocular blood flow in experimental glaucoma. Almasieh M, MacIntyre JN, Pouliot M, et al. Invest. Ophthalmol. Vis. Sci. 54(5), 3171-83, (2013)
Pd-catalyzed asymmetric allylic etherification using chiral biphenol-based diphosphinite ligands and its application for the formal total synthesis of (-)-galanthamine. Zang Y and Ojima I J. Org. Chem. 78(8), 4013-8, (2013)
Physostigmine and galanthamine bind in the presence of agonist at the canonical and noncanonical subunit interfaces of a nicotinic acetylcholine receptor. Hamouda AK, Kimm T, and Cohen JB J. Neurosci. 33(2), 485-94, (2013)
Endogenous acetylcholine rescues NMDA-induced long-lasting hippocampal cell damage via stimulation of muscarinic M(1) receptors: elucidation using organic hippocampal slice cultures. Inada C, Thi Le X, Tsuneyama K, et al. Eur. J. Pharmacol. 699(1-3), 150-9, (2013)
Use of rivastigmine or galantamine and risk of adverse cardiac events: a database study from the Netherlands. Kröger E, Berkers M, Carmichael PH, et al. Am. J. Geriatr. Pharmacother. 10(6), 373-80, (2012)
Effect on cognition of galanthamine administered for neuromuscular block reversal in octogenarians undergoing cataract surgery. Cozanitis D, Keinonen M, and Maunuksela EL Anaesthesiol. Intensive Ther. 44(2), 76-80, (2012)
Metabolic studies of the Amaryllidaceous alkaloids galantamine and lycorine based on electrochemical simulation in addition to in vivo and in vitro models. Jahn S, Seiwert B, Kretzing S, et al. Anal. Chim. Acta 756, 60-72, (2012)
Mapping of the interaction sites of galanthamine: a quantitative analysis through pairwise potentials and quantum chemistry. Galland N, Kone S, and Le Questel JY J. Comput. Aided Mol. Des. 26(10), 1111-26, (2012)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?