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G1774 Sigma

Glucagon

≥95% (HPLC), powder, synthetic

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines Growth Factors and Hormones (Obesity), Cytokines, Growth Factors and Hormones, Gastrointestinal Peptides,
biological source   synthetic
InChI Key   RKGLLHCSSVJTAN-YYICOITRSA-N
assay   ≥95% (HPLC)
form   powder
storage temp.   −20°C
Gene Information   human ... GCG(2641)

Description

Amino Acid Sequence

His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr

Components

H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-OH.xHCl

Other Notes

Lyophilized from 0.1% TFA in H2O

Application

Glucagon (GCG) has been used-
• as a component of hormone stock solution for preserving full biological activity of heart tissues obtained from male Sprague-Dawley rats
• as an infusion in phases II and III fasting king penguins to study the various lipolytic, metabolic, and hormonal responses

Biochem/physiol Actions

Glucagon (GCG) produces elevation in contractility and the frequency of contraction in heart muscles. It activates PI3K (phosphoinositide 3-kinase) and thus, elevates glucose utilization by heart muscles. In multiple mammals, though not humans, this peptide induces lipolysis, and is the major lipolytic hormone in birds. It also induces gluconeogenesis and glycogenolysis in mammals and birds.

General description

Glucagon (GCG) peptide is secreted in response to insulin from pancreatic islets α-cells.

Price and Availability


Amplified Detection

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

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Product #

Description

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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