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G1792 Sigma

GITR Ligand human

>97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder

Synonym: GITRL, Glucocorticoid-induced TNF ligand

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Properties

Related Categories Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones,
recombinant   expressed in baculovirus infected Sf21 cells
assay   >97% (SDS-PAGE)
form   lyophilized powder
mol wt   calculated mol wt 15 kDa
  mol wt 14-16 kDa by SDS-PAGE (triplet)
impurities   endotoxin, tested
storage temp.   −20°C
Gene Information   human ... TNFSF18(8995)

Description

Analysis Note

The biological activity is measured by its ability to bind human GITR.

Other Notes

N-terminal histidine-tagged extracellular domain.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 1.25 mg bovine serum albumin.

Biochem/physiol Actions

Type II transmembrane protein in the TNF superfamily. Appears to act in conjunction with the GITR, to protect T cells against activation induced cell death.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
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