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G3907 Sigma

Glutathione−Agarose

set of 3 pre-packed columns (2.5 ml each)

Synonym: GSH-agarose, S-linked glutathione agarose

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Properties

Related Categories Affinity Chromatography, GST, Glutathione, Glutathione S-transferase (GST), Molecular Biology,
packaging   set of 3 pre-packed columns (2.5 ml each)
matrix   cross-linked 4% beaded agarose
storage temp.   2-8°C

Description

Application

Affinity chromatography using glutathione-agarose permits rapid, mild, non-denaturing and highly selective purification of proteins containing glutathione binding sequences, such as Glutathione S-Transferase (GST), glutathione peroxidase and glyoxalase I.

Affinity chromatography using glutathione-agarose permits rapid, mild, non-denaturing and highly selective purification of glutathione binding enzymes such as glutathione-S-transferase, glutathione peroxidase, and glyoxalase I.
The product was used in the design, synthesis and biological evaluation of new tryptamine and tetrahydro-β-carboline-based selective inhibitors of CDK4. It was also used to study Fascaplysin-inspired diindolyls as selective inhibitors of CDK4/cyclin D1.

Linkage

Suspension of Product No. G 4510

Physical form

Suspension in 0.5 M NaCl and 20% ethanol

General description

The resin in these columns consists of glutathione attached through the sulfur to epoxy activated, 4% cross-linked beaded agarose resulting in a 12 atom spacer.

Price and Availability


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Safety & Documentation

Safety Information

WGK Germany 
3
Flash Point(F) 
179.6 °F
Flash Point(C) 
82 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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