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G4535 Sigma

[D-Lys3]-GHRP-6

synthetic, lyophilized powder

Synonym: His-D-Trp-D-Lys-Trp-D-Phe-Lys-NH2, [D-Lys3]-Growth Hormone Releasing Peptide 6, [His1, D-Lys3, Lys6]-GHRP

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, GH-RH, Growth Hormone Releasing Factors, Neuropeptides,
biological source   synthetic
InChI Key   MGSNWNLPMHXGDD-DFWOJPNQSA-N
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... GHRH(2691)

Description

Amino Acid Sequence

His-Trp-Lys-Trp-Phe-Lys-NH2

Application

[D-Lys3]-GHRP6 has been used-
• to treat bovine somatotropes to determine the release of GH from treated cells and non-treated or control cells
• for intraperitoneal injection to groups of broiler chicken to determine the effect on feed intake, weight gain, and feed conversion ratio

Biochem/physiol Actions

[D-Lys3]-GHRP6 (growth hormone releasing peptide 6) induces the secretion of growth hormone (GH). In the membrane of clonal GC somatotropes, this peptide elevates the number of functional voltage-gated Ca2+ and Na+ channels. Chronic treatment with this peptide causes an elevation in Na+ macroscopic current in bovine pituitary somatotropes in culture, which results in an increase in the release of GH.

General description

[D-Lys3]-GHRP6 (growth hormone releasing peptide 6) is a synthetic analog of the orexigenic peptide hormone called ghrelin.

Price and Availability


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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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