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G4753 Sigma

Griseofulvin

from Penicillium griseofulvum, 97.0-102.0%

Synonym: (2S)-trans-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro(benzofuran-2[3H],1′-[2]cyclohexene)-3,4′-dione

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Bioactive Small Molecule Alphabetical Index,
biological source   from Penicillium griseofulvum
InChI Key   DDUHZTYCFQRHIY-RBHXEPJQSA-N
assay   97.0-102.0%
form   powder
antibiotic activity spectrum   fungi
storage temp.   −20°C

Description

Biochem/physiol Actions

Antifungal. Mode of action: Disrupts the mitotic spindle structure and inhibits nuclear division. Induces apoptosis in human tumor cell lines.

Packaging

5, 25, 50 g in poly bottle

Price and Availability


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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
WG9800000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Antifungals

Antifungal compounds have been overshadowed by antibacterials in research interest and application due to the greater impact bacterial infections have had on health. Resistance to antibacterial drugs...
Chloe McClanahan
BioFiles 2009, 4.3, 10.
Keywords: Antibiotics, Antifungals, Cellular processes, Clinical, Fungicides, Gene expression, Research Reports, Transcription

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Peer-Reviewed Papers
15

References

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