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G5002 Sigma

Gramicidin from Bacillus aneurinolyticus (Bacillus brevis)

Linear polypeptide antibiotic complex. A mixture of gramicidins A, B, C, and D.

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Description

Packaging

1, 5 g in glass bottle

100, 500 mg in glass bottle

Biochem/physiol Actions

Linear polypeptide antibiotic, a mixture of gramicidin A, B, C, and D. Gramicidin D, a channel-forming ionophore that flip-flops slowly across the membrane is a known Pgp substrate and surprisingly was found to inhibit Pgp ATPase activity. This inhibition was reversed by other Pgp substrates suggesting a common drug binding site among MDR substrate-type drugs and chemosensitizers.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
MD8225000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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