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G5779 Sigma

Gly-Pro-Arg-Pro amide

≥97% (HPLC)

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Description

Amino Acid Sequence

Gly-Pro-Arg-Pro-NH2

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Application

Gly-Pro-Arg-Pro amide has been used-
• as a constituent of buffer during fluid-phase and bound thrombin inhibition assays, to determine the activity of thrombin
• for blocking fibrin polymerization and preventing fibrin clot formation in presence of α-thrombin, in blood obtained from mice
• during preparation of human soluble fibrin, to block the polymerization of soluble fibrin

Biochem/physiol Actions

Gly-Pro-Arg-Pro peptide suppresses the early steps of fibrin polymerization. The amide derivative of this peptide prevents the degradation of fibrinogen and fragment D by plasmin, even in the presence of EGTA (ethylene glycol-bis(β-aminoethyl ether)-N,N,N′,N′-tetraacetic acid).

General description

Gly-Pro-Arg-Pro is a peptide that mimics the N-terminal Gly-Pro-Arg region in the a chain of fibrin protein.

Price and Availability


Amplified Detection

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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