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G6013 Sigma

L-Glutathione reduced

cell culture tested, BioReagent, ≥98.0%, powder

Synonym: γ-L-Glutamyl-L-cysteinyl-glycine, GSH

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Properties

Related Categories Allium cepa (Onion), Amino Acids, Amino Acids and Vitamins, Antioxidant, Cell Biology,
Quality Level   PREMIUM
InChI Key   RWSXRVCMGQZWBV-WDSKDSINSA-N
product line   BioReagent
assay   ≥98.0%
form   powder
mp   192-195 °C (dec.)(lit.)
solubility   H2O: soluble50 mg/mL
suitability   cell culture tested
storage temp.   2-8°C

Description

Amino Acid Sequence

γ-Glu-Cys-Gly

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Application

May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.

Biochem/physiol Actions

Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.

Packaging

5, 10, 25, 100 g in poly bottle

Price and Availability


Filter out uncertainty.

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
MC0556000
Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

Peer-Reviewed Papers
15

References

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