|Related Categories||Antioxidant and Free Radical Scavengers, Antioxidants and Cytoprotectants, Bioactive Small Molecules, Bioflavonoids, Cancer Research,|
|solubility||H2O: soluble5 mg/mL (with brief sonication)|
Polyphenolic compound found in green tea. An epimer of (−)-epigallocatechin.
Possesses free radical scavenging ability. Inhibits the growth and adherence of P. gingivalis onto the buccal epithelial cells.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26-36|
Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
BioFiles 2007, 2.2, 2.
Keywords: Adhesion, Anti-inflammatory agents, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins
Inhibitory mechanism of pancreatic amyloid fibril formation: formation of the complex between tea catechins and the fragment of residues 22-27. Kamihira-Ishijima M, Nakazawa H, Kira A, et al. Biochemistry 51(51), 10167-74, (2012)
Combination therapy of dexamethasone with epigallocatechin enhances tibiotarsal bone articulation and modulates oxidative status correlates with cartilage cytokines expression in the early phase of experimental arthritis. Roy S, Sannigrahi S, Ghosh B, et al. Eur. J. Pharmacol. 698(1-3), 444-54, (2013)
Green tea catechins increase the force of contraction in isolated Guinea pig atrial muscle preparations by increasing the amplitude of intracellular ca(2+) concentration. Sasaki T, Kamata R, Ueno S, et al. J. Vet. Med. Sci. 74, 1603-1608, (2012)
A novel combination of methotrexate and epigallocatechin attenuates the overexpression of pro-inflammatory cartilage cytokines and modulates antioxidant status in adjuvant arthritic rats. Roy S, Sannigrahi S, Vaddepalli RP, et al. Inflammation 35(4), 1435-47, (2012)
Quercetin and epigallocatechin gallate effects on the cell membranes biophysical properties correlate with their antioxidant potential. Margina D, Ilie M, Manda G, et al. Gen. Physiol. Biophys. 31(1), 47-55, (2012)
Inactivation of prolyl hydroxylase domain (PHD) protein by epigallocatechin (EGCG) stabilizes hypoxia-inducible factor (HIF-1α) and induces hepcidin (Hamp) in rat kidney. Manalo DJ, Baek JH, Buehler PW, et al. Biochem. Biophys. Res. Commun. 416(3-4), 421-6, (2011)
Bioactivity-guided identification and cell signaling technology to delineate the lactate dehydrogenase A inhibition effects of Spatholobus suberectus on breast cancer. Wang Z, Wang D, Han S, et al. PLoS ONE 8(2), e56631, (2013)
A proprietary topical preparation containing EGCG-stearate and glycerin with inhibitory effects on herpes simplex virus: case study. Zhao M, Jiang J, Zheng R, et al. Inflamm. Allergy Drug Targets 11(5), 364-8, (2012)
EGCG suppresses prostate cancer cell growth modulating acetylation of androgen receptor by anti-histone acetyltransferase activity. Lee YH, Kwak J, Choi HK, et al. Int. J. Mol. Med. 30(1), 69-74, (2012)
[Mechanism of interaction between risperidone and tea catechin (2) influence of presence of galloyl group in catechin on insoluble complex formation with risperidone]. Ikeda H, Moriwaki H, Matsubara T, et al. Yakugaku Zasshi 132(1), 145-53, (2012)
Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis. Rathore K, Choudhary S, Odoi A, et al. Carcinogenesis 33(1), 174-83, (2012)
[Integrated pharmacokinetic study of multiple effective components of tea polyphenols and its correlation with anti-free radical pharmacodynamics in rats]. Li QS, Xi H, Han GZ, et al. Yao Xue Xue Bao 47(7), 863-9, (2012)
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