EMAIL THIS PAGE TO A FRIEND
G7420 Sigma

Galectin-1 human

recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder

Purchase

Properties

Related Categories Adhesion Molecules and Related Proteins, Cell Biology, Cell Signaling and Neuroscience, Cytoskeleton and Extracellular Matrix, Galectins,
recombinant   expressed in E. coli
assay   ≥95% (SDS-PAGE)
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... LGALS1(3956)

Description

Biochem/physiol Actions

Galectin-1 has been implicated in metastasis and aggregation of cancer cells based on its association with the glycoprotein 90K. Galectin-1 may play a significant role in cancer through apoptosis, cell adhesion and migration, regulation of the cell cycle and tumor evasion of immune responses.

Galectin-1 has been implicated in metastasis and aggregation of cancer cells based on its association with the glycoprotein 90K. Galectin-1 may play a significant role in cancer through apoptosis, cell adhesion, migration, cell cycle regulation and tumor evasion of immune responses.

General description

Galectin-1 is a member of the family of animal lectins, which selectively binds β-galactoside residues.

Physical form

Lyophilized from a 5 mg/mL solution in phosphate buffered saline containing 8 mM DTT and 150 mM lactose.

Application

A common function of galectins is to cross-link structures containing N-acetyl-lactosamine located at the cell surface and within the extracellular matrix. They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. They have variable affinity for more complex oligosaccharides. Other activities of galectin-1 include cell differentiation and inhibition of CD45 protein phosphatase activity.

Price and Availability


Amplified Detection
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Galectins

Galectins are a family of animal carbohydrate binding proteins; the name is from their description as β-galactoside-specific lectins. They have been strongly implicated in inflammation and cancer and...
BioFiles 2007, 2.1, 21.
Keywords: Adhesion, Anti-inflammatory agents, Apoptosis, Biochemistry, Cancer, Cell signaling, Inflammation, Ligands, Methods, Type, transformation

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

related product

Product #

Description

Add to Cart

HPA000646 Anti-LGALS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?