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  • G7914 - Anti-Glycogen Synthase Kinase-3β (GSK-3β) antibody produced in rabbit

G7914 Sigma

Anti-Glycogen Synthase Kinase-3β (GSK-3β) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution


Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies for Neural Stem Cells,
species reactivity   rat, human
application(s)   microarray: suitable
  western blot: 1:2,000 using rat brain extract
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt 46 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... GSK3B(2932)
rat ... Gsk3b(84027)
biological source   rabbit
conjugate   unconjugated



Synthetic peptide corresponding to amino acids 403-420 of human glycogen synthase kinase 3 β (GSK3β), coupled to KLH. It is identical in rat and highly conserved in frog and zebrafish GSK3β.

General description

Glycogen synthase kinase-3 β (GSK3β) is a 47kD protein that belongs to serine/ threonine protein kinase family and is expressed ubiquitously as a constitutively active kinase. It has a pivotal role in regulating the degradation of β-catenin by the tumor suppressor gene product APC. Anti-Glycogen Synthase Kinase-3β (GSK-3β) antibody can be used in microarray. Rabbit anti- GSK3β antibody reacts specifically with rat GSK3β but not with GSK3α.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide.


Anti-Glycogen Synthase Kinase-3β (GSK-3β) antibody can be used in western blotting (diluted 1:2000) using cytosolic fraction of rat brain extract.

Price and Availability

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