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G8001 Sigma

Glycine ethyl ester hydrochloride


Synonym: Ethyl glycinate hydrochloride

  • CAS Number 623-33-6

  • Linear Formula NH2CH2COOC2H5 · HCl

  • Molecular Weight 139.58

  •  Beilstein Registry Number 3594034

  •  EC Number 210-787-4

  •  MDL number MFCD00012871

  • Popular Documents:  FTNMR (PDF)  



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This product has been replaced by G6503-ALDRICH | Glycine ethyl ester hydrochloride 99%

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GHS05  GHS05
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WGK Germany 


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Protocols & Articles

Peer-Reviewed Papers


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Role of amphibian egg transglutaminase in the development of secondary cytostatic factor in vitro. Zhang J and Masui Y Mol. Reprod. Dev. 47(3), 302-11, (1997)


Mutations in M2 alter the selectivity of the mouse nicotinic acetylcholine receptor for organic and alkali metal cations. Cohen BN, Labarca C, Davidson N, et al. J. Gen. Physiol. 100(3), 373-400, (1992)


Novel micelles from graft polyphosphazenes as potential anti-cancer drug delivery systems: drug encapsulation and in vitro evaluation. Zheng C, Qiu L, Yao X, et al. Int. J. Pharm. 373(1-2), 133-40, (2009)


Thermally responsive polymeric micelles self-assembled by amphiphilic polyphosphazene with poly(N-isopropylacrylamide) and ethyl glycinate as side groups: polymer synthesis, characterization, and in vitro drug release study. Zhang JX, Qiu LY, Jin Y, et al. J. Biomed. Mater. Res. A 76(4), 773-80, (2006)


Lipophilic prodrugs of amino acids and vitamin E as osmolytes for the compensation of hyperosmotic stress in human keratinocytes. Graf R, Kock M, Bock A, et al. Exp. Dermatol. 18(4), 370-7, (2009)


Doxorubicin-loaded polymeric micelles based on amphiphilic polyphosphazenes with poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide) and ethyl glycinate as side groups: synthesis, preparation and in vitro evaluation. Qiu LY, Wu XL, and Jin Y Pharm. Res. 26(4), 946-57, (2009)


Aldimine to ketoamine isomerization (Amadori rearrangement) potential at the individual nonenzymic glycation sites of hemoglobin A: preferential inhibition of glycation by nucleophiles at sites of low isomerization potential. Acharya AS, Roy RP, and Dorai B J. Protein Chem. 10(3), 345-58, (1991)


Assembly properties of tubulin after carboxyl group modification. Mejillano MR and Himes RH J. Biol. Chem. 266(1), 657-64, (1991)


Novel micro-crosslinked poly(organophosphazenes) with improved mechanical properties and controllable degradation rate as potential biodegradable matrix. Cui Y, Zhao X, Tang X, et al. Biomaterials 25(3), 451-7, (2004)


Effects of chemical modification of Anabaena flavodoxin and ferredoxin-NADP+ reductase on the kinetics of interprotein electron transfer reactions. Medina M, Gomez-Moreno C, and Tollin G Eur. J. Biochem. 210(2), 577-83, (1992)


Mass spectrometry-based protein footprinting characterizes the structures of oligomeric apolipoprotein E2, E3, and E4. Gau B, Garai K, Frieden C, et al. Biochemistry 50(38), 8117-26, (2011)


An active-site peptide containing the second essential carboxyl group of dextransucrase from Leuconostoc mesenteroides by chemical modifications. Funane K, Shiraiwa M, Hashimoto K, et al. Biochemistry 32(49), 13696-702, (1993)


Transglutaminase covalently incorporates amines into human immunodeficiency virus envelope glycoprotein gp120 in vitro. Mariniello L, Esposito C, Gentile V, et al. Int. J. Pept. Protein Res. 42(2), 204-6, (1993)


Physicochemical characterization, in vitro, and in vivo evaluation of indomethacin-loaded nanocarriers self-assembled by amphiphilic polyphosphazene. Zhang JX, Li SH, Li XH, et al. J. Biomed. Mater. Res. A 86(4), 914-25, (2008)


Amidation of basic carboxyl groups of hemoglobin. Rao MJ and Acharya AS Meth. Enzymol. 231, 246-67, (1994)


Nitrosation of glycine ethyl ester and ethyl diazoacetate to give the alkylating agent and mutagen ethyl chloro(hydroximino)acetate. Zhou L, Haorah J, Chen SC, et al. Chem. Res. Toxicol. 17(3), 416-23, (2004)


Modification of aldehyde dehydrogenase with dicyclohexylcarbodiimide: separation of dehydrogenase from esterase activity. Abriola DP and Pietruszko R J. Protein Chem. 11(1), 59-70, (1992)


Identification of the sites of modification on bovine carbonic anhydrase II (BCA II) by the salt-bridge reagent cyanogen, C2N2. Ghenbot G, Emge T, and Day RA Biochim. Biophys. Acta 1161(1), 59-65, (1993)


Amino acids and glycine ethyl ester as new crystallization reagents for lysozyme. Ito L, Shiraki K, and Yamaguchi H Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66(Pt 6), 750-4, (2010)


The conversion of tubulin carboxyl groups to amides has a stabilizing effect on microtubules. Mejillano MR, Tolo ET, Williams RC, et al. Biochemistry 31(13), 3478-83, (1992)


Kinetic isotope effects and ligand binding in PQQ-dependent methanol dehydrogenase. Hothi P, Sutcliffe MJ, and Scrutton NS Biochem. J. 388(Pt 1), 123-33, (2005)


alpha(2)-plasmin inhibitor is a substrate for tissue transglutaminase: an in vitro study. Hevessy Z, Patthy A, Kárpáti L, et al. Thromb. Res. 99(4), 399-406, (2000)


Pharmacologic evaluation of factor XIIIa*-like enzyme activity in equine plasma as a potential therapeutic avenue for the inhibition of fibrinous tissue. Coyne CP, Smith JE, and DeBowes RM Am. J. Vet. Res. 53(5), 695-705, (1992)


Identification of the aspartic acid residue located at or near substrate-binding site of rye seed chitinase-c. Yamagami T and Funatsu G Biosci. Biotechnol. Biochem. 62(2), 383-5, (1998)


Investigation of the skin sensitizing properties of 5 osmolytic prodrugs in a weight-of-evidence assessment, employing in silico, in vivo, and read across analyses. Scheel J and Keller D Int. J. Toxicol. 31(4), 358-63, (2012)


Beil. 4,II,780

FT-IR 2 (1), 1120:D / FT-IR 1 (1), 671:D / FT-NMR 1 (1), 1067:B / IR-Spectra (2), 349:A / IR-Spectra (3), 393:G / NMR-Reference 2 (1), 566:D / RegBook 1 (1), 769:B / Sigma FT-IR 1 (1), 177:D / Structure Index 1, 119:A:7

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G6503 Glycine ethyl ester hydrochloride, 99%

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