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G8032 Sigma

Gelsolin from bovine plasma

>95% (SDS-PAGE), lyophilized powder

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Description

Biochem/physiol Actions

Gelsolin is an actin-severing protein found in mammalian cells and blood plasma. Exhibits tumor suppressor activity in several cancer cell lines and in nude mice.

Gelsolin is an actin-binding protein that regulates the assembly and disassembly of actin filaments.

Packaging

0.2, 0.5 mg in glass bottle

Package size based on protein content

Unit Definition

One unit will reduce viscosity difference between actin solution and buffer by 50% in a 1 mL mixture containing 1-2mg F-actin, 0.15 M KCl, 20 mM Tris, pH 7.6, 0.2 mM CaCl2, 0.2 mM ATP, and 1 mM DTT at 28 °C.

Physical form

Lyophilized powder containing NaCl, Tris buffer salt, and EGTA

Application

Gelsolin from bovine plasma was used in actin assembly assays.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

Peer-Reviewed Papers
15

References

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