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G8041 Sigma

Galanin-Like Peptide Fragment 1-60 porcine trifluoroacetate salt

≥95% (HPLC), solid

  • CAS Number 245114-96-9

  • Empirical Formula (Hill Notation) C281H443N81O78

  • Molecular Weight 6204.02

  •  MDL number MFCD03456908

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Galanins, Neuropeptides, Peptides and Proteins,
assay   ≥95% (HPLC)
form   solid
storage temp.   −20°C
Gene Information   pig ... GALP(396772)

Description

Amino Acid Sequence

Ala-Pro-Val-His-Arg-Gly-Arg-Gly-Gly-Trp-Thr-Leu-Asn-Ser-Ala-Gly-Tyr-Leu-Leu-Gly-Pro-Val-Leu-His- Pro-Pro-Ser-Arg-Ala-Glu-Gly-Gly-Gly-Lys-Gly-Lys-Thr-Ala-Leu-Gly-Ile-Leu-Asp-Leu-Trp-Lys-Ala-Ile-Asp-Gly-Leu-Pro-Tyr-Pro-Gln-Ser-Gln-Leu-Ala-Ser

Biochem/physiol Actions

Endogenous ligand that preferentially binds to the GalR2 galanin receptor.

GALP-(1–60) peptide binds with high affinity to galanin receptor (GALR2). This peptide is thought to play a role in mediating the actions of leptin, a satiety hormone. It is a potent vasoactive peptide and is thought to be involved in inflammatory responses.

General description

Galanin-like peptide (GALP) is a GALR2 (galanin receptor)-binding neuropeptide, which is produced by pig hypothalamus. This peptide is produced as 120-residue GALP precursor protein, and is processed to a 60-residue peptide, with a non-amidated C-terminal.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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