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G9023 Sigma

Goat serum

Synonym: Serum

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Description

Frequently Asked Questions

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Application

Normal goat serum may be used as a blocking agent or negative control in immunoassays. For immunohistochemistry and immunocytochemistry, goat serum was used between 1%-20% as blocking agent in various studies.1,2,3,4,5,6,7

General description

Goat serum is pooled from a normal donor herd.

Price and Availability

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Safety & Documentation

Safety Information

Personal Protective Equipment 
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

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Peer-Reviewed Papers

References

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1. Perfusion-decellularized matrix: using nature's platform to engineer a bioartificial heart Ott HC et al Nat. Med. 14, 213-21, (2008)

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2. Performance of a time-resolved fluorescence immunoassay for measuring Varicella-Zoster Virus Immunoglobulin G levels in adults and comparison with commercial enzyme immunoassays and Merck Glycoprotein Enzyme Immunoassay Maple PAC et al Clin. Vaccine Immunol. 13, 214-8, (2006)

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3. Expression of α-smooth muscle actin in canine intervertebal disc cells in situ and in collagen-glycosaminoglycan matrices in vitro Schneider TO et al J. Orthop. Res. 17, 192-9, (1999)

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4. Pressure-induced changes in axial eye length of chick and tree shrew: significance of myofibroblasts in the sclera Phillips JR and McBrien NA Invest. Ophthalmol. Vis. Sci. 45, 758-63, (2004)

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5. Estrogen receptor-mediated activation of the serum response element in MCF-7 cells through MAPK-dependent phosphorylation of Elk-1 Duan R et al J. Biol. Chem. 276, 11590-8, (2001)

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6. Meniscus structure in human, sheep, and rabbit for animal models of meniscus repair Chevrier A et al J. Orthop. Res. 27, 1197-203, (2009)

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7. Axonal transport and cytoskeletal changes in the laminar regions after elevated intraocular pressure Balaratnasingam C et al Invest. Ophthalmol. Vis. Sci. 48, 3632-44, (2007)

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A Genome-Wide RNAi Screen to Dissect Centriole Duplication and Centrosome Maturation in Drosophila Baum, B., et al. PLoS Biol. 6, e224, (2008)

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Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis. Parisiadou L J. Neurosci. 29(44), 13971-80, (2009)

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TGF-β-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORγt function. Liang Zhou et al Nature 453, 236-40, (2008)

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Novel roles of hakai in cell proliferation and oncogenesis. Figueroa A Mol. Biol. Cell 20(15), 3533-42, (2009)

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A novel mouse model of Alzheimer's disease with chronic estrogen deficiency leads to glial cell activation and hypertrophy. Annik Prat et al J. Aging Res. 2011, 251517, (2011)

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α-Synuclein impairs macroautophagy: implications for Parkinson's disease. Winslow AR, Chen CW, Corrochano S, et al. J. Cell Biol. 190(6), 1023-37, (2010)

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Autophagy is required and protects against apoptosis during myoblast differentiation. McMillan EM and Quadrilatero J Biochem. J. 462(2), 267-77, (2014)

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Autonomous onset of the circadian clock in the zebrafish embryo. Dekens MP EMBO J. 27(20), 2757-65, (2008)

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Effect of heparan sulfate and gold nanoparticles on muscle development during embryogenesis. Marlena Zielinska et al Int. J. Nanomedicine 6, 3163-72, (2011)

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APP anterograde transport requires Rab3A GTPase activity for assembly of the transport vesicle. A Szodorai et al J. Neurosci. 29, 14534-44, (2010)

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Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis. Stephan H Nucleic Acids Res. 37(18), 6028-41, (2009)

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Interaction of E-cadherin and PTEN regulates morphogenesis and growth arrest in human mammary epithelial cells. Marcia V. Fournier et al Cancer Res. 69, 4545-52, (2009)

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The directionality of the nuclear transport of the influenza A genome is driven by selective exposure of nuclear localization sequences on nucleoprotein. Wu WW Virol. J. 6, 68, (2009)

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Mast cells contribute to the stromal microenvironment in mammary gland branching morphogenesis. Lilla JN Dev. Biol. 337(1), 124-33, (2010)

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ZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing over. Adelman CA and Petrini JH PLoS Genet. 4(3), e1000042, (2008)

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Huntingtin mediates dendritic transport of β-actin mRNA in rat neurons. Ma B, Savas JN, Yu MS, et al. Sci. Rep. 1, 140, (2011)

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Corticosteroids reverse cytokine-induced block of survival and differentiation of oligodendrocyte progenitor cells from rats. Mann SA J. Neuroinflammation 5, 39, (2008)

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The cytoplasmic domain of proEGF negatively regulates motility and elastinolytic activity in thyroid carcinoma cells. Glogowska A Neoplasia 10(10), 1120-30, (2008)

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Role for herpes simplex virus 1 ICP27 in the inhibition of type I interferon signaling. Johnson KE, Song B, and Knipe DM Virology 374(2), 487-94, (2008)

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Immunohistochemistry in the evaluation of neovascularization in tumor xenografts. Dezhi Wang et al Biotech. Histochem. 83, 179-89, (2009)

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Screening the expression of ABCB6 in erythrocytes reveals an unexpectedly high frequency of Lan mutations in healthy individuals. Koszarska M, Kucsma N, Kiss K, et al. PLoS ONE 9(10), e111590, (2014)

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