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G9415 Sigma

Anti-GFRα-2 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym: Anti-GDNF receptor-β, Anti-GDNFR-β, Anti-NTNR-α, Anti-RETL2, Anti-TmR2, Anti-neurturin receptor-α

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies to Cytokines and Growth Factors,
species reactivity   mouse, human, rat
application(s)   western blot: 1-2 μg/mL using human HeLa cell extract
clone   polyclonal
antibody form   IgG fraction of antiserum
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... GFRA2(2675)
mouse ... Gfra2(14586)
rat ... Gfra2(25136)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 377-391 of human GFRα-2.

General description

GDNF family receptor α (GFR α) is a glycosylphos phatidylinositol (GPI)-anchored protein that belongs to GDNFR family. GFR α expresses mainly in nervous system. It behaves as a co-receptor to activate Ret and can facilitates the GDNF, NTN, PSP, and ART signaling. GDNF binds preferentially to GFR α-1, NTN to GFR α -2, ART to GFR α -3, and PSP to GFR α-4. Rabbit anti-GFRα-2 antibody reacts specifically with mouse, rat or human GFR α 2.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide

Application

Anti-GFR α-2 antibody can be used in western blotting (1-2 μg/mL) using human HeLa cell extract.

Price and Availability


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