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G9910 Sigma

Sodium glycodeoxycholate

BioXtra, ≥97% (TLC)

Synonym: 3α,12α-Dihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Glycodeoxycholic acid sodium salt, Glycodesoxycholic acid, N-(3α,12α-Dihydroxy-24-oxocholan-24-yl)glycine

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Properties

Related Categories Anionic Detergents, Bile Salts, Biochemicals and Reagents, Cell Culture, Detergents,
description   anionic
InChI Key   BMYWWGPEKRLDGW-ZXMGEDLUSA-N
product line   BioXtra
assay   ≥97% (TLC)
impurities   ≤0.001% Phosphorus (P)
  ≤0.1% Insoluble matter
solubility   H2O: soluble0.1 M, clear, colorless
anion traces   chloride (Cl-): ≤1%
  sulfate (SO42-): ≤0.05%
cation traces   Al: ≤0.0005%
  Ca: ≤0.005%
  Cu: ≤0.0005%
  Fe: ≤0.001%
  K: ≤0.005%
  Mg: ≤0.001%
  NH4+: ≤0.05%
  Pb: ≤0.001%
  Zn: ≤0.0005%

Description

Biochem/physiol Actions

Induces apoptosis in hepatocytes; may induce DNA cleavage.

General description

Sodium glycodeoxycholate is a bile salt that can be used to form biomimicking environments.

Other Notes

Bile Salt

Application

Sodium glycodeoxycholate has been used in a study to develop more similar mimetic intestinal fluids to physiological fluids than those developed by mixed bile salt systems (MBS). It has also been used in a study to investigate Ca2+ buffering capability of bile salt micelles.

Price and Availability

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, Transcription

Bile Salts and Bile Salt Hydrolase

Several Lactobacillus and Bifidobacterium probiotic strains exhibit bile salt hydrolase (BSH) activity and are suspected to play a role in combating the negative effects of bile via detoxification of...
Chloe McClanahan
Biofiles Edition 6.2
Keywords: Detoxification, Probiotics, Thin layer chromatography, Titrations

Probiotics and Human Health

At the beginning of the 20th century, probiotics were thought to have a beneficial effect to the host by improving the intestinal microbial balance. Through his studies and observations, the Russian ...
Chloe McClanahan
BioFiles Edition 6.2
Keywords: AGE, Absorption, Adhesion, Amplification, Anaerobic, Antimicrobials, Apoptosis, Cancer, Capillary electrophoresis, Carcinogens, Cell culture, Cell proliferation, Chromatography, Coagulation, Detoxification, Diagnostic, Diseases, Enzyme activity, Fermentation, Gas chromatography, Gastrointestinal, Genomics, High performance liquid chromatography, Immunology, Inflammation, Magnetic resonance spectroscopy, Metabolism, Metabolites, Microbiology, Molecular biology, Nucleic acid hybridization, Pharmaceutical, Phosphorylations, Polymerase chain reaction, Polymerase chain reaction - quantitative, Prebiotics, Probiotics, Reductions, Respiratory, Sequencing, Thin layer chromatography, Titrations

Peer-Reviewed Papers
15

References

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