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H0540 Sigma

Anti-Hepatocyte Growth Factor antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-HGF

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Pancreatic Stem Cells, Antibodies for Stem Cell Biology,
species reactivity   mouse
application(s)   capture ELISA: 0.2-0.8 μg/mL
  immunohistochemistry: 5-15 μg/mL
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   mouse ... Hgf(15234)
biological source   goat
conjugate   unconjugated

Description

Immunogen

purified, NSO cell-derived recombinant mouse hepatocyte growth factor.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Biochem/physiol Actions

Hepatocyte Growth Factor (HGF) is a multifunctional, heparin-binding factor that stimulates the proliferation of liver cells. The cellular effects of HGF are mediated by its receptor, c-Met, that leads to significant activation of ERK, Src/FAK, STAT3 and PI3K signaling. Various functions of the HGF/c-Met signaling include proliferation, cell survival, motility and adhesion and tissue regeneration. Apart from liver, HGF also mediates regeneration of kidney, lung and gastro-intestines.

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Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  1
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers
15

References

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H7157 Anti-Hepatocyte Growth Factor antibody produced in goat, affinity isolated antibody, lyophilized powder
H0652 Anti-Hepatocyte Growth Factor antibody produced in goat, IgG fraction of antiserum, lyophilized powder

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