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  • H0646 - Anti-HVEM (Herpes virus entry mediator) antibody produced in goat

H0646 Sigma

Anti-HVEM (Herpes virus entry mediator) antibody produced in goat

affinity isolated antibody, lyophilized powder



Related Categories Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology, Antibodies to Cytokines and Growth Factors,
species reactivity   human
application(s)   indirect ELISA: 0.5-1 μg/mL
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... TNFRSF14(8764)
biological source   goat
conjugate   unconjugated



recombinant human HVEM (herpes virus entry mediator) extracellular domain derived from NS0 cells.

General description

Herpes virus entry mediator (HVEM) also known as ATAR (another TRAF-associated receptor) or TR2 (TNF receptor-like molecule) is a 45kD (approx.) type I membrane protein that belongs to TNF receptor superfamily and is expressed mainly in peripheral blood T cells, B cells, monocytes as well as in tissues enriched in lymphoid cells. During infection it facilitates the herpes virus entry into cell and can inhibit the activation, proliferation and cytokine production of T cells. HVEM interacts with its cellular ligand LIGHT and controls immune response by inducing cell death and cell activation. Anti-HVEM (Herpes virus entry mediator) antibody can be used in indirect ELISA (working concentration:-0.5-1.0 μg/ml). Goat anti-HVEM reacts specifically with recombinant human HVEM. The antibody exhibits no cross-reactivity with recombinant human NGF, TNF sRI and TNF sRII receptor.

Physical form

Lyophilized from 0.2 μm filtered phosphate buffered saline.


The antibody does not cross-react with recombinant human TNF sRI, recombinant human TNF sRII, and recombinant human NGF-R.


Anti-HVEM (Herpes virus entry mediator) antibody may be used for immunoblotting at a working antibody concentration of 0.1-0.2 μg/ml for detecting human HVEM.

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