|Related Categories||Aminoglycosides, Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antibiotics by Application,|
|sterility||0.22 μm filtered|
|concentration||45-60 mg/mL in H2O|
Hygromycin has been used to select drug-resistant stable transfectants after transfer of the hygromycin phosphotransferase gene in a variety of cell culture applications.
Hygromycin B is an aminoglycoside antibiotic produced by the bacterium Streptomyces hygroscopicus that kills bacteria, fungi and higher eukaryotic cells by inhibiting protein synthesis. It is used for the selection and maintenance of prokaryotic and eukaryotic cells that contain the hygromycin resistance gene. It is used in gene transfer experiments as a selection agent. Product H0654 is a solution that comes ≥60% (HPAE) and 45-60 mg/mL in H2O.
Antibacterial and antifungal. Mode of action: Inhibition of protein synthesis, by inducing the misreading of the m-RNA template in prokaryotes and eukaryotes. It selectively penetrates cells that have been rendered permeable by virus infection.
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Certificate of Analysis
Certificate of Origin
|Symbol||GHS05, GHS06, GHS08|
|Hazard statements||H301 + H311-H318-H330-H334|
|Precautionary statements||P260-P280-P284-P301 + P310-P305 + P351 + P338-P310|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter|
|Hazard Codes (Europe)||T+|
|Risk Statements (Europe)||26/27/28-41-42/43|
|Safety Statements (Europe)||23-26-28-36/37/39-45|
|RIDADR||UN 2810 6.1/PG 1|
Increasing antibiotic resistance and the lack of new drug development have hindered the success of antibiotics in recent years. Staph aureus is susceptible to a number of antibiotics with various mec...
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