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H0656 Sigma

HCC-1 human

≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested

Synonym: Hemofiltrate CC chemokine-1, M-CIF, Macrophage Colony Inhibition Factor

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones,
recombinant   expressed in E. coli
assay   ≥97% (SDS-PAGE)
form   lyophilized powder
impurities   endotoxin, tested
suitability   cell culture tested
storage temp.   −20°C
Gene Information   human ... CCL14(6358)

Description

Analysis Note

The biological activity is measured by its ability to chemoattract cultured human monocytes or BaF/3 hCCR1 transfected cells.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.5 mg bovine serum albumin.

Biochem/physiol Actions

HCC-1, a member of the C-C, or β chemokine class, is a 8.7 kDa, non-glycosylated polypeptide of 74 amino acids. Mature HCC-1 is produced by cleavage of a 19 amino acid signal peptide from the precursor HCC-1 (93 amino acids). HCC-1 is expressed constitutively in normal tissues and is present in high concentrations in human plasma. It shows approximately 46% amino acid identity with MIP-1α and MIP-1β, and 29-37% sequence identity with other C-C chemokines.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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