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H0879 Sigma

Hexamethonium bromide

Synonym: Hexane-1,6-bis(trimethylammonium bromide), N,N,N,N′,N′,N′-Hexamethylhexamethylenediammonium dibromide

  • CAS Number 55-97-0

  • Linear Formula (CH3)3N(Br)(CH2)6N(Br)(CH3)3

  • Molecular Weight 362.19

  •  Beilstein Registry Number 3715749

  •  EC Number 200-249-7

  •  MDL number MFCD00011787

  •  PubChem Substance ID 24278459

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Properties

Related Categories Antagonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   FAPSXSAPXXJTOU-UHFFFAOYSA-L
mp   282-285 °C (dec.)
Gene Information   human ... CHRNA1(1134), CHRNA10(57053), CHRNA2(1135), CHRNA3(1136), CHRNA4(1137), CHRNA5(1138), CHRNA6(8973), CHRNA7(1139), CHRNA9(55584), CHRNB1(1140), CHRNB2(1141), CHRNB3(1142), CHRNB4(1143)

Description

Biochem/physiol Actions

Preferentially blocks nicotinic receptors at autonomic ganglia; crosses blood-brain barrier only at high doses.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

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Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
BQ8575000
Protocols & Articles
Peer-Reviewed Papers
15

References

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