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H1009 Sigma

Hydrogen peroxide solution

30 % (w/w) in H2O, contains stabilizer

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Description

Frequently Asked Questions

Live Chat and Frequently Asked Questions are available for this Product.

Packaging

5, 100, 500 mL in poly bottle

Application

Used to prepare solutions for induction of apoptosis. ~60% of HL60 cells were apoptotic after exposure to 15 μM H2O2 for 8 hr.1

Features and Benefits

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Price and Availability


DISCOVER Bioactive Small Molecules

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Hydrogen peroxide solution

contains inhibitor, 30 wt. % in H2O, meets USP testing specifications

Hydrogen peroxide solution

contains inhibitor, 30 wt. % in H2O, ACS reagent

Hydrogen peroxide solution

50 wt. % in H2O, stabilized

Hydrogen peroxide solution

35 wt. % in H2O

Hydrogen peroxide solution

contains ~200 ppm acetanilide as stabilizer, 3 wt. % in H2O

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2014 8(5.1) / PGII
WGK Germany 
1

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Determination of Water Content in Hydrogen peroxide 35% Using Karl Fischer Titration

Metal peroxides react with the KF reagents and form water. They cannot be titrated directly. Hydroperoxides form iodine and an equivalent amount of water. An interference will therefore not occur. Di...
Keywords: Titrations

Protocols

4-Chloro-1-Naphthol Solution Protocol

Solution contains 0.48 mM 4-Chloro-1-Naphthol, 50 mM Tris-HCl and 0.2 M NaCl in 17% methanol. This is a substrate solution designed for visualizing horseradish peroxidase conjugates in Western Blotti...
Keywords: Western blot

Enzymatic Assay of Catalase (EC 1.11.1.6)

The continuous spectrophotometric rate reduction determination (A240, Light path = 1 cm) is based on the following reaction:
Keywords: Reductions

Enzymatic Assay of Peroxidase (EC 1.11.1.7) 2,2'-Azino-bis(3-Ethylbenzthiazoline-6-Sulfonic Acid) as a Substrate

Replaces SPABTS02. Procedure updated to conform to current QUMAS formatting guidelines. Refer to CR SOP-DEK-ENZ42.
Keywords: Extinction coefficient

Enzymatic Assay of Peroxidase (EC 1.11.1.7)

This procedure is for the determination of Peroxidase enzymatic activity using Pyrogallol as the substrate. Products using this method include, but are not limited to, P1709, P2088, P6140, P6782, P81...
Keywords: Enzymology, Extinction coefficient, Gene expression, Size-exclusion chromatography

Peer-Reviewed Papers

References

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FKBP51 And Cyp40 Are Positive Regulators Of Androgen-dependent Prostate Cancer Cell Growth And The Targets Of FK506 And Cyclosporin A. Periyasamy, S., et al. Oncogene 29, 1691-701, (2010)

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Alkylation Of The Tumor Suppressor PTEN Activates Akt And β-catenin Signaling: A Mechanism Linking Inflammation And Oxidative Stress With Cancer. Covey, T.M., et al. PLoS ONE 5, e13545, (2010)

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Heterologous Ferredoxin Reductase And Flavodoxin Protect Cos-7 Cells From Oxidative Stress. Mediavilla, M.G., et al. PLoS ONE 5, e13501, (2010)

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Calpain-mediated Degradation Of Reversibly Oxidized Protein-tyrosine Phosphatase 1B. Trümpler, A., et al. FASEB J. 276, 5622-33, (2009)

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Effects Of Menadione, Hydrogen Peroxide, And Quercetin On Apoptosis And Delayed Luminescence Of Human Leukemia Jurkat T-cells. Baran, I., et al. Cell Biochem. Biophys. 58, 169-79, (2010)

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Adaptation Of NS Cells Growth And Differentiation To High-throughput Screening-compatible Plates. Garavaglia, A., et al. BMC Neurosci. 11, 7, (2010)

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CC-chemokine Ligand 18/pulmonary Activation-regulated Chemokine Expression In The CNS With Special Reference To Traumatic Brain Injuries And Neoplastic Disorders. Chang, C.Y., et al. Neuroscience 165, 1233-43, (2010)

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Effect Of Hydrogen Peroxide On Potassium Currents In Inner Hair Cells Isolated From Guinea Pig Cochlea. Kimitsuki, T., et al. Neuroreport 21, 1045-9, (2010)

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The small molecule GMX1778 is a potent inhibitor of NAD+ biosynthesis: strategy for enhanced therapy in nicotinic acid phosphoribosyltransferase 1-deficient tumors. Watson M Mol. Cell. Biol. 29(21), 5872-88, (2009)

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Improved arsenic(III) adsorption by Al2O3 nanoparticles and H2O2: evidence of oxidation to arsenic(V) from X-ray absorption spectroscopy. Önnby L, Kumar PS, Sigfridsson KG, et al. Chemosphere 113, 151-7, (2014)

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Application of electrochemical advanced oxidation processes to the mineralization of the herbicide diuron. Pipi AR, Sirés I, De Andrade AR, et al. Chemosphere 109, 49-55, (2014)

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Involvement of the nuclear high mobility group B1 peptides released from injured hepatocytes in murine hepatic fibrogenesis. Kao YH, Lin YC, Tsai MS, et al. Biochim. Biophys. Acta 1842(9), 1720-32, (2014)

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[Reduction of bad breath from the periodontal patients by dilute hydrogen peroxide solution (author's transl)]. Kaizu T, Sato H, Shiozaki A, et al. Nihon Shishubyo Gakkai Kaishi 20(3), 260-6, (1978)

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Penetration and cytotoxicity of a bleaching gel activated by LED/laser in restored teeth. Parreiras S, Mena-Serrano A, Moreira CG, et al. Am. J. Dent. 27(6), 301-6, (2014)

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Longterm melatonin administration alleviates paraquat mediated oxidative stress in Drosophila melanogaster. Medina-Leendertz S, Paz M, Mora M, et al. Invest. Clin. 55(4), 352-64, (2014)

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Estrogen modulates intestinal mucus physiochemical properties and protects against oxidant injury. Diebel ME, Diebel LN, Manke CW, et al. J. Trauma Acute Care Surg. 78(1), 94-9, (2015)

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Redox biology: signaling via a peroxiredoxin sensor. Winterbourn CC and Hampton MB Nat. Chem. Biol. 11(1), 5-6, (2015)

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Highly efficient oxidation of secondary alcohols to ketones catalyzed by manganese complexes of N4 ligands with H2O2. Shen D, Miao C, Xu D, et al. Org. Lett. 17(1), 54-7, (2015)

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Molecular investigation of iron-sulfur cluster assembly scaffolds under stress. Blanc B, Clémancey M, Latour JM, et al. Biochemistry 53(50), 7867-9, (2014)

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Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension. Chettimada S, Gupte R, Rawat D, et al. Am. J. Physiol. Lung Cell. Mol. Physiol. 308(3), L287-300, (2015)

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Application of the Fenton process in the elimination of helminth eggs. Escobar-Megchún SI, Nájera-Aguilar HA, González-Hilerio M, et al. J. Water Health 12(4), 722-6, (2014)

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Cooperative substrate binding by a diguanylate cyclase. Oliveira MC, Teixeira RD, Andrade MO, et al. J. Mol. Biol. 427(2), 415-32, (2015)

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DJ-1 regulates the expression of renal (pro)renin receptor via reactive oxygen species-mediated epigenetic modification. Lee DY, Kim HS, Won KJ, et al. Biochim. Biophys. Acta 1850(2), 426-34, (2015)

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Mechanism of H₂O₂-induced oxidative stress regulating viability and biocontrol ability of Rhodotorula glutinis. Chen J, Li B, Qin G, et al. Int. J. Food Microbiol. 193, 152-8, (2015)

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Membranous adenylyl cyclase 1 activation is regulated by oxidation of N- and C-terminal methionine residues in calmodulin. Lübker C, Urbauer RJ, Moskovitz J, et al. Biochem. Pharmacol. 93(2), 196-209, (2015)

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Response of direct or priming defense against Botrytis cinerea to methyl jasmonate treatment at different concentrations in grape berries. Wang K, Liao Y, Kan J, et al. Int. J. Food Microbiol. 194, 32-9, (2015)

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Stem cell factor (SCF) protects osteoblasts from oxidative stress through activating c-Kit-Akt signaling. Yang L, Wu Z, Yin G, et al. Biochem. Biophys. Res. Commun. 455(3-4), 256-61, (2014)

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Neuroprotection by Kukoamine A against oxidative stress may involve N-methyl-D-aspartate receptors. Hu XL, Gao LY, Niu YX, et al. Biochim. Biophys. Acta 1850(2), 287-98, (2015)

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Reactive oxygen species in human semen: validation and qualification of a chemiluminescence assay. Vessey W, Perez-Miranda A, Macfarquhar R, et al. Fertil. Steril. 102(6), 1576-83.e4, (2014)

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An evaluation of genotoxicity in human neuronal-type cells subjected to oxidative stress under an extremely low frequency pulsed magnetic field. Giorgi G, Lecciso M, Capri M, et al. Mutat. Res. Genet. Toxicol. Environ. Mutagen. 775-776, 31-7, (2014)

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Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling. Sobotta MC, Liou W, Stöcker S, et al. Nat. Chem. Biol. 11(1), 64-70, (2015)

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Disulfide-mediated stabilization of the IκB kinase binding domain of NF-κB essential modulator (NEMO). Zhou L, Yeo AT, Ballarano C, et al. Biochemistry 53(50), 7929-44, (2014)

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REVOLUTA and WRKY53 connect early and late leaf development in Arabidopsis. Xie Y, Huhn K, Brandt R, et al. Development 141(24), 4772-83, (2014)

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Overlapping and complementary oxidative stress defense mechanisms in nontypeable Haemophilus influenzae. Harrison A, Baker BD, and Munson RS J. Bacteriol. 197(2), 277-85, (2015)

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Acute exertion elicits a H2O2-dependent vasodilator mechanism in the microvasculature of exercise-trained but not sedentary adults. Durand MJ, Dharmashankar K, Bian JT, et al. Hypertension 65(1), 140-5, (2015)

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Infantile hypertrophic pyloric stenosis (IHPS): a study of its pathophysiology utilizing the newborn hph-1 mouse model of the disease. Welsh C, Shifrin Y, Pan J, et al. Am. J. Physiol. Gastrointest. Liver Physiol. 307(12), G1198-206, (2014)

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Specific recognition of guanines in non-duplex regions of nucleic acids with potassium tungstate and hydrogen peroxide. Mao W, Xu X, He H, et al. Nucleic Acids Res. 43(1), e3, (2015)

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Selenoprotein H suppresses cellular senescence through genome maintenance and redox regulation. Wu RT, Cao L, Chen BP, et al. J. Biol. Chem. 289(49), 34378-88, (2014)

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Polyphenols from green tea prevent antineuritogenic action of Nogo-A via 67-kDa laminin receptor and hydrogen peroxide. Gundimeda U, McNeill TH, Barseghian BA, et al. J. Neurochem. 132(1), 70-84, (2015)

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Oral streptococci and nitrite-mediated interference of Pseudomonas aeruginosa. Scoffield JA and Wu H Infect. Immun. 83(1), 101-7, (2015)

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Exogenous application of methyl jasmonate lowers the effect of cadmium-induced oxidative injury in rice seedlings. Singh I and Shah K Phytochemistry 108, 57-66, (2014)

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Exendin-4 alleviates angiotensin II-induced senescence in vascular smooth muscle cells by inhibiting Rac1 activation via a cAMP/PKA-dependent pathway. Zhao L, Li AQ, Zhou TF, et al. Am. J. Physiol. Cell Physiol. 307(12), C1130-41, (2014)

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Effects of metal ions and hydrogen peroxide on the phenotype of yeast hom6Δ mutant. Tun NM, Lennon BR, O'Doherty PJ, et al. Lett. Appl. Microbiol. 60(1), 20-6, (2015)

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An acute rise in intraluminal pressure shifts the mediator of flow-mediated dilation from nitric oxide to hydrogen peroxide in human arterioles. Beyer AM, Durand MJ, Hockenberry J, et al. Am. J. Physiol. Heart Circ. Physiol. 307(11), H1587-93, (2014)

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Overproduction of stromal ferredoxin:NADPH oxidoreductase in H2O 2-accumulating Brassica napus leaf protoplasts. Tewari RK, Satoh M, Kado S, et al. Plant Mol. Biol. 86(6), 627-39, (2014)

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Involvement of PG2212 zinc finger protein in the regulation of oxidative stress resistance in Porphyromonas gingivalis W83. Dou Y, Aruni W, Luo T, et al. J. Bacteriol. 196(23), 4057-70, (2014)

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Influence of l-carnosine on pro-antioxidant status in elite kayakers and canoeists. Slowinska-Lisowska M, Zembron-Lacny A, Rynkiewicz M, et al. Acta Physiol. Hung. 101(4), 461-70, (2014)

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Determining the minimum inhibitory concentration of Tetraclean against Candida albicans. Qyasian A, Mohammadi Z, Giardino L, et al. Niger. J. Med. 23(3), 201-6, (2014)

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Pneumococcal hydrogen peroxide-induced stress signaling regulates inflammatory genes. Loose M, Hudel M, Zimmer KP, et al. J. Infect. Dis. 211(2), 306-16, (2015)

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The timing and operational management of the variables of bleaching in cases of rehabilitation in the esthetic field. Sibilla P, Cogo E, Turrini R, et al. Int. J. Esthet. Dent. 9(3), 436-45, (2014)

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Differential role of ethylene and hydrogen peroxide in dark-induced stomatal closure. Kar RK, Parvin N, and Laha D Pak. J. Biol. Sci. 16(24), 1991-6, (2013)

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Isolation of Streptomyces globisporus and Blakeslea trispora mutants with increased carotenoid content. Matselyukh BP, Matselyukh DY, Golembiovska SL, et al. Mikrobiol. Z. 75(6), 10-6, (2013)

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Tooth colour change with Ozicure Oxygen Activator: a comparative in vitro tooth bleaching study. Grundlingh AA, Grossman ES, and Witcomb MJ SADJ 67(7), 332-7, (2012)

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[Reactive oxygen forms and Ca ions as possible intermediaries under the induction of heat resistance of plant cells by jasmonic acid]. Karpets IuV, Kolupaev IuE, Iastreb TO, et al. Ukr. Biokhim. Zh. 85(3), 62-8, (2013)

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Integration of wetland wastewater treatment with disinfection via bioelectrochemical H2O2 production. Arends JB, Van Denhouwe S, De Vrieze J, et al. Commun. Agric. Appl. Biol. Sci. 78(1), 173-7, (2013)

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[Reseach of oxidative stress induces aging in rabbit intervertebral disc nucleus pulposus cells injured by H2O2]. Xie J, Tong PJ, Shan LT, et al. Zhongguo Gu Shang 26(4), 332-5, (2013)

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[Microorganisms from carbonate oil deposits in Romashkinskoe oil field and their biotechnological potential ]. Nazina TN, Pavlova NK, Tatarkin IuV, et al. Mikrobiologiia 82(2), 191-202, (2013)

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[Potentiometric glucose determination in human serum samples with glucose oxidase biosensor based on iodide electrode]. Karakus E, Pekyardimchi Sh, and Kilich E Prikl. Biokhim. Mikrobiol. 49(2), 209-14, (2013)

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[Molecular mechanisms of gradient sensing in mesenchymal cells]. Tiurin-Kuz'min PA, Vorotnikov AV, and Tkachuk VA Ross. Fiziol. Zh. Im. I. M. Sechenova 99(3), 294-312, (2013)

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Capsaicin short term administration effect on different immune parameters. Iancu AD, Petcu I, Radu BM, et al. Roum. Arch. Microbiol. Immunol. 71(4), 221-54, (2012)

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Double transgenic mice--a suitable model for studying oxidative stress in type 1 diabetes mellitus. Iancu AD and Stăvaru C Roum. Arch. Microbiol. Immunol. 71(4), 201-20, (2012)

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Prevalence of lactobacilli in normal women and women with bacterial vaginosis. Chooruk A, Utto P, Teanpaisan R, et al. J. Med. Assoc. Thai. 96(5), 519-22, (2013)

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[Protective effect and mechanism of astragaloside IV on oxidative stress injury of mesangial cells]. Cao LL, Li WZ, Si XL, et al. Zhongguo Zhong Yao Za Zhi 38(5), 725-30, (2013)

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Production of high concentrations of H2O2 in a bioelectrochemical reactor fed with real municipal wastewater. Modin O and Fukushi K Environ. Technol. 34(17-20), 2737-42, (2013)

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Hydrogen peroxide: a signaling messenger. Stone JR and Yang S Antioxid. Redox Signal. 8(3-4), 243-70, (2006)

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Super-suppression of mitochondrial reactive oxygen species signaling impairs compensatory autophagy in primary mitophagic cardiomyopathy. Song M, Chen Y, Gong G, et al. Circ. Res. 115(3), 348-53, (2014)

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Targeting SOD1 reduces experimental non–small-cell lung cancer. Glasauer A, Sena LA, Diebold LP, et al. J. Clin. Invest. 124(1), 117-28, (2014)

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APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress. Willis J, Patel Y, Lentz BL, et al. Proc. Natl. Acad. Sci. U. S. A. 110(26), 10592-7, (2013)

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Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats. Nicolai A Hypertension 53(3), 508-15, (2009)

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A multi-marker assay to distinguish malignant melanomas from benign nevi. Kashani-Sabet M Proc. Natl. Acad. Sci. U. S. A. 106(15), 6268-72, (2009)

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Cytotoxicity of mitochondria-targeted resveratrol derivatives: interactions with respiratory chain complexes and ATP synthase. Sassi N, Mattarei A, Azzolini M, et al. Biochim. Biophys. Acta 1837(10), 1781-9, (2014)

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Long-term superior performance of a stem cell/hepatocyte device for the treatment of acute liver failure. Yagi H, Parekkadan B, Suganuma K, et al. Tissue Eng. Part A 15(11), 3377-88, (2009)

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Dual role of hydrogen peroxide in cancer: possible relevance to cancer chemoprevention and therapy. López-Lázaro M Cancer Lett. 252(1), 1-8, (2007)

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Genetic and physiological effects of noncoherent visible light combined with hydrogen peroxide on Streptococcus mutans in biofilm. Doron Steinberg et al Antimicrob. Agents Chemother. 52, 2626-31, (2008)

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Hypothermia protects human neurons. Antonic A, Dottori M, Leung J, et al. Int. J. Stroke 9(5), 544-52, (2014)

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Sodium channels contribute to degeneration of dorsal root ganglion neurites induced by mitochondrial dysfunction in an in vitro model of axonal injury. Persson AK, Kim I, Zhao P, et al. J. Neurosci. 33(49), 19250-61, (2013)

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Layer-by-layer immobilized catalase on electrospun nanofibrous mats protects against oxidative stress induced by hydrogen peroxide. Huang R, Deng H, Cai T, et al. J. Biomed. Nanotechnol. 10(7), 1346-58, (2014)

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β-catenin activation promotes liver regeneration after acetaminophen-induced injury. Udayan Apte et al Am. J. Pathol. 175, 1056-65, (2009)

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Cytochrome bd oxidase from Escherichia coli displays high catalase activity: an additional defense against oxidative stress. Borisov VB, Forte E, Davletshin A, et al. FEBS Lett. 587(14), 2214-8, (2013)

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Regulation of the intracellular localization of Foxo3a by stress-activated protein kinase signaling pathways in skeletal muscle cells. Clavel S Mol. Cell. Biol. 30(2), 470-80, (2010)

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Localization of vascular adhesion protein-1 (VAP-1) in the human eye. Lama Almulki et al Exp. Eye Res. 90, 26-32, (2009)

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Highly stereoselective epoxidation with H2O2 catalyzed by electron-rich aminopyridine manganese catalysts. Cussó O, Garcia-Bosch I, Font D, et al. Org. Lett. 15(24), 6158-61, (2013)

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Citric acid improves lead (pb) phytoextraction in brassica napus L. by mitigating pb-induced morphological and biochemical damages. Shakoor MB, Ali S, Hameed A, et al. Ecotoxicol. Environ. Saf. 109, 38-47, (2014)

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Mitochondrial bioenergetics deregulation caused by long-chain 3-hydroxy fatty acids accumulating in LCHAD and MTP deficiencies in rat brain: a possible role of mPTP opening as a pathomechanism in these disorders? Tonin AM, Amaral AU, Busanello EN, et al. Biochim. Biophys. Acta 1842(9), 1658-67, (2014)

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Influence of Pseudomonas aeruginosa as PGPR on oxidative stress tolerance in wheat under Zn stress. Islam F, Yasmeen T, Ali Q, et al. Ecotoxicol. Environ. Saf. 104, 285-93, (2014)

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Exogenous jasmonic acid can enhance tolerance of wheat seedlings to salt stress. Qiu Z, Guo J, Zhu A, et al. Ecotoxicol. Environ. Saf. 104, 202-8, (2014)

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Degradation of diclofenac by ultrasonic irradiation: kinetic studies and degradation pathways. Nie E, Yang M, Wang D, et al. Chemosphere 113, 165-70, (2014)

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Physiological and molecular level effects of silver nanoparticles exposure in rice (Oryza sativa L.) seedlings. Nair PM and Chung IM Chemosphere 112, 105-13, (2014)

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Carbon and chlorine isotope fractionation during Fenton-like degradation of trichloroethene. Liu Y, Gan Y, Zhou A, et al. Chemosphere 107, 94-100, (2014)

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Development of standardized methods for assessing biocidal efficacy of contact lens care solutions against Acanthamoeba trophozoites and cysts. Kilvington S and Lam A Invest. Ophthalmol. Vis. Sci. 54(7), 4527-37, (2013)

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Protection from oxidative stress relies mainly on derepression of OxyR-dependent KatB and Dps in Shewanella oneidensis. Jiang Y, Dong Y, Luo Q, et al. J. Bacteriol. 196(2), 445-58, (2014)

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Superoxide constitutes a major signal of mitochondrial superoxide flash. Zhang X, Huang Z, Hou T, et al. Life Sci. 93(4), 178-86, (2013)

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Supplemental L-arginine and vitamins E and C preserve xanthine oxidase activity in the lung of broiler chickens grown under hypobaric hypoxia. Bautista-Ortega J, Cortes-Cuevas A, Ellis EA, et al. Poult. Sci. 93(4), 979-88, (2014)

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Hydrogen peroxide as a paracrine vascular mediator: regulation and signaling leading to dysfunction. Ardanaz N and Pagano PJ Exp. Biol. Med. (Maywood.) 231(3), 237-51, (2006)

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Xanthohumol modulates inflammation, oxidative stress, and angiogenesis in type 1 diabetic rat skin wound healing. Costa R, Negrão R, Valente I, et al. J. Nat. Prod. 76(11), 2047-53, (2013)

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Intracellular hydrogen peroxide and superoxide poison 3-deoxy-D-arabinoheptulosonate 7-phosphate synthase, the first committed enzyme in the aromatic biosynthetic pathway of Escherichia coli. Sobota JM, Gu M, and Imlay JA J. Bacteriol. 196(11), 1980-91, (2014)

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Oxidative stress mediates the conversion of endothelial cells into myofibroblasts via a TGF-β1 and TGF-β2-dependent pathway. Montorfano I, Becerra A, Cerro R, et al. Lab. Invest. 94(10), 1068-82, (2014)

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β-amyloid fibrils in Alzheimer disease are not inert when bound to copper ions but can degrade hydrogen peroxide and generate reactive oxygen species. Mayes J, Tinker-Mill C, Kolosov O, et al. J. Biol. Chem. 289(17), 12052-62, (2014)

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Polychlorinated biphenyl-induced oxidative stress in organotypic co-cultures: experimental dopamine depletion prevents reductions in GABA. Lyng GD Neurotoxicology 29(2), 301-8, (2008)

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Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures. Simeone KA, Matthews SA, Samson KK, et al. Exp. Neurol. 251, 84-90, (2014)

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Hydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neurotoxicity. Narasimhan M, Riar AK, Rathinam ML, et al. Toxicol. Lett. 228(3), 179-91, (2014)

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Hydrogen peroxide regulates the cholinergic signal in a concentration dependent manner. Schallreuter KU and Elwary S Life Sci. 80(24-25), 2221-6, (2007)

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A single residue, arginine 65, is critical for the functional interaction of leukocyte-associated inhibitory receptor-1 with collagens. Xiaobin Tang et al J. Immunol. 182, 5446-52, (2009)

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Hydrogen peroxide tooth-whitening (bleaching) products: review of adverse effects and safety issues. Tredwin CJ, Naik S, Lewis NJ, et al. Br. Dent. J. 200(7), 371-6, (2006)

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Bromodomain and extraterminal proteins suppress NF-E2-related factor 2-mediated antioxidant gene expression. Michaeloudes C, Mercado N, Clarke C, et al. J. Immunol. 192(10), 4913-20, (2014)

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Ethyl acetate extract of germinated brown rice attenuates hydrogen peroxide-induced oxidative stress in human SH-SY5Y neuroblastoma cells: role of anti-apoptotic, pro-survival and antioxidant genes. Azmi NH, Ismail N, Imam MU, et al. BMC Complement Altern. Med. 13, 177, (2013)

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Expression of peroxiredoxins I and IV in multiple myeloma: association with immunoglobulin accumulation. Demasi AP, Martinez EF, Napimoga MH, et al. Virchows Arch. 463(1), 47-55, (2013)

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Mechanistic characterization of a 2-thioxanthine myeloperoxidase inhibitor and selectivity assessment utilizing click chemistry--activity-based protein profiling. Ward J, Spath SN, Pabst B, et al. Biochemistry 52(51), 9187-201, (2013)

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An efficient TiO2 coated immobilized system for the degradation studies of herbicide isoproturon: durability studies. Verma A, Prakash NT, and Toor AP Chemosphere 109, 7-13, (2014)

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Activation of ER stress by hydrogen peroxide in C2C12 myotubes. Pierre N, Barbé C, Gilson H, et al. Biochem. Biophys. Res. Commun. 450(1), 459-63, (2014)

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Syk interacts with and phosphorylates nucleolin to stabilize Bcl-x(L) mRNA and promote cell survival. Wang WH, Childress MO, and Geahlen RL Mol. Cell. Biol. 34(20), 3788-99, (2014)

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Methylation by NSun2 represses the levels and function of microRNA 125b. Yuan S, Tang H, Xing J, et al. Mol. Cell. Biol. 34(19), 3630-41, (2014)

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Preparation and application of graphene-poly (diallyldimethylammoniumchloride)-iron oxide nanoparticles buckypaper for hydrogen peroxide detection. You X, Kim J, Pak YK, et al. J. Nanosci. Nanotechnol. 13(11), 7349-57, (2013)

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Dentin hypersensitivity after teeth bleaching with in-office systems. Randomized clinical trial. Martin J, Fernandez E, Bahamondes V, et al. Am. J. Dent. 26(1), 10-4, (2013)

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The periplasmic disulfide oxidoreductase DsbA contributes to Haemophilus influenzae pathogenesis. Rosadini CV, Wong SM, and Akerley BJ Infect. Immun. 76(4), 1498-508, (2008)

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Cigarette smoke extract (CSE) delays NOD2 expression and affects NOD2/RIPK2 interactions in intestinal epithelial cells. Aldhous MC, Soo K, Stark LA, et al. PLoS ONE 6(9), e24715, (2011)

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Technical and economic feasibility of polyester dyeing wastewater treatment by coagulation/flocculation and Fenton's oxidation. Rodrigues CS, Boaventura RA, and Madeira LM Environ. Technol. 35(9-12), 1307-19, (2014)

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Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC. Haidari M, Zhang W, and Wakame K Life Sci. 93(25-26), 994-1003, (2013)

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Caenorhabditis elegans PI3K mutants reveal novel genes underlying exceptional stress resistance and lifespan. Ayyadevara S Aging Cell 8(6), 706-25, (2009)

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Antioxidant protection by American ginseng in pancreatic beta-cells. Lin E, Wang Y, Mehendale S, et al. Am. J. Chin. Med. 36(5), 981-8, (2008)

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High-performance liquid chromatographic method for the direct quantitation of oxy radicals in myocardium and blood by means of 1,3-dimethylthiourea and dimethyl sulfoxide. Rao PS, Rujikarn N, and Luber JM J. Chromatogr. A 459, 269-73, (1988)

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Redox regulation of MMP-3/TIMP-1 ratio in intestinal myofibroblasts: effect of N-acetylcysteine and curcumin. Fontani F, Marcucci T, Picariello L, et al. Exp. Cell Res. 323(1), 77-86, (2014)

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Diabetes-induced increase of renal medullary hydrogen peroxide and urinary angiotensinogen is similar in normotensive and hypertensive rats. Patinha D, Afonso J, Sousa T, et al. Life Sci. 108(2), 71-9, (2014)

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Protective effect of piperine on electrophysiology abnormalities of left atrial myocytes induced by hydrogen peroxide in rabbits. Liu Y, Zhang Y, Lin K, et al. Life Sci. 94(2), 99-105, (2014)

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Ruthenium nanocatalysis on redox reactions. Veerakumar P, Ramdass A, and Rajagopal S J. Nanosci. Nanotechnol. 13(7), 4761-86, (2013)

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Synthesis of sugars embodying conjugated carbonyl systems and related triazole derivatives from carboxymethyl glycoside lactones. Evaluation of their antimicrobial activity and toxicity. Nuno M Xavier et al Bioorg. Med. Chem. 19, 926-38, (2011)

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Gene expression in snapbeans exposed to ozone and protected by ethylenediurea. Paoletti E, Castagna A, Ederli L, et al. Environ. Pollut. 193, 1-5, (2014)

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Effect of mild-temperature H2O2 oxidation on solubilization and anaerobic digestion of waste activated sludge. Junga H, Kim J, Lee S, et al. Environ. Technol. 35(13-16), 1702-9, (2014)

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Application of intensified Fenton oxidation to the treatment of sawmill wastewater. Munoz M, Pliego G, de Pedro ZM, et al. Chemosphere 109, 34-41, (2014)

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The effect of catalase on migration and invasion of lung cancer cells by regulating the activities of cathepsin S, L, and K. Tsai JY, Lee MJ, Dah-Tsyr Chang M, et al. Exp. Cell Res. 323(1), 28-40, (2014)

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Electrochemical sensing of H2O2 by the modified electrode with pd nanoparticles on multi-walled carbon nanotubes-g-poly(lactic acid). Han HS, You JM, Jeong H, et al. J. Nanosci. Nanotechnol. 14(6), 4050-7, (2014)

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Cannabidiol improves vasorelaxation in Zucker diabetic fatty rats through cyclooxygenase activation. Wheal AJ, Cipriano M, Fowler CJ, et al. J. Pharmacol. Exp. Ther. 351(2), 457-66, (2014)

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Advanced oxidation of bromide-containing drinking water: a balance between bromate and trihalomethane formation control. Wang Y, Yu J, Han P, et al. J. Environ. Sci. (China) 25(11), 2169-76, (2013)

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Removal of benzotriazole by heterogeneous photoelectro-Fenton like process using ZnFe2O4 nanoparticles as catalyst. Wu J, Pu W, Yang C, et al. J. Environ. Sci. (China) 25(4), 801-7, (2013)

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Comet Assay on Daphnia magna in eco-genotoxicity testing. Pellegri V, Gorbi G, and Buschini A Aquat. Toxicol. 155, 261-8, (2014)

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Rpi-blb2-mediated late blight resistance in Nicotiana benthamiana requires SGT1 and salicylic acid-mediated signaling but not RAR1 or HSP90. Oh SK, Kim H, and Choi D FEBS Lett. 588(7), 1109-15, (2014)

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Redox systems in Botrytis cinerea: impact on development and virulence. Viefhues A, Heller J, Temme N, et al. Mol. Plant Microbe Interact. 27(8), 858-74, (2014)

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Reduction of an E. coli O157:H7 and Salmonella composite on fresh strawberries by varying antimicrobial washes and vacuum perfusion. Gurtler JB, Bailey RB, Jin TZ, et al. Int. J. Food Microbiol. 189, 113-8, (2014)

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Glucosamine protects nucleus pulposus cells and induces autophagy via the mTOR-dependent pathway. Jiang L, Jin Y, Wang H, et al. J. Orthop. Res. 32(11), 1532-42, (2014)

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Do antioxidants inhibit oxidative-stress-induced autophagy of tenofibroblasts? Kim RJ, Hah YS, Sung CM, et al. J. Orthop. Res. 32(7), 937-43, (2014)

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Synthesis and in vitro antitumor activity of asperphenamate derivatives as autophagy inducer. Lei Yuan et al Bioorg. Med. Chem. Lett. 22, 2216-20, (2012)

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Low-cost preparation of photoluminescent carbon nanodots and application as peroxidase mimetics in colorimetric detection of H2O2 and glucose. Wu D, Deng X, Huang X, et al. J. Nanosci. Nanotechnol. 13(10), 6611-6, (2013)

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Periplasmic disulfide isomerase DsbC is involved in the reduction of copper binding protein CueP from Salmonella enterica serovar Typhimurium. Yoon BY, Kim JS, Um SH, et al. Biochem. Biophys. Res. Commun. 446(4), 971-6, (2014)

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MiR-92a regulates viability and angiogenesis of endothelial cells under oxidative stress. Zhang L, Zhou M, Qin G, et al. Biochem. Biophys. Res. Commun. 446(4), 952-8, (2014)

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Toxicity assessment of tannery effluent treated by an optimized photo-Fenton process. Borba FH, Módenes AN, Espinoza-Quiñones FR, et al. Environ. Technol. 34(5-8), 653-61, (2013)

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Modified Fenton oxidation of diesel fuel in arctic soils rich in organic matter and iron. Sherwood MK and Cassidy DP Chemosphere 113, 56-61, (2014)

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Mycorrhizal fungi modulate phytochemical production and antioxidant activity of Cichorium intybus L. (Asteraceae) under metal toxicity. Rozpądek P, Wężowicz K, Stojakowska A, et al. Chemosphere 112, 217-24, (2014)

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Myocardial ischemic reperfusion induces de novo Nrf2 protein translation. Xu B, Zhang J, Strom J, et al. Biochim. Biophys. Acta 1842(9), 1638-47, (2014)

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Integration of advanced oxidation processes at mild conditions in wet scrubbers for odourous sulphur compounds treatment. Vega E, Martin MJ, and Gonzalez-Olmos R Chemosphere 109, 113-9, (2014)

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N-Acetylcysteine increases corneal endothelial cell survival in a mouse model of Fuchs endothelial corneal dystrophy. Kim EC, Meng H, and Jun AS Exp. Eye Res. 127, 20-5, (2014)

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A wheat lipid transfer protein 3 could enhance the basal thermotolerance and oxidative stress resistance of Arabidopsis. Wang F, Zang XS, Kabir MR, et al. Gene 550(1), 18-26, (2014)

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Treatment of steam-assisted gravity drainage water using low coagulant dose and Fenton oxidation. Al-As'ad A and Husein MM Environ. Technol. 35(13-16), 1630-8, (2014)

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Fluorescent ZnCdS nanoparticles for glucose sensing. Kochubey VI, Volkova EK, and Konyukhova JG J. Biomed. Opt. 19(1), 011020, (2014)

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The RNA exosome affects iron response and sensitivity to oxidative stress. Tsanova B, Spatrick P, Jacobson A, et al. RNA 20(7), 1057-67, (2014)

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Compensatory effects of hOGG1 for hMTH1 in oxidative DNA damage caused by hydrogen peroxide. Ke Y, Lv Z, Yang X, et al. Toxicol. Lett. 230(1), 62-8, (2014)

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Development of an in vitro test system for assessment of male, reproductive toxicity. Habas K, Anderson D, and Brinkworth M Toxicol. Lett. 225(1), 86-91, (2014)

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The role of NAD(+)-dependent isocitrate dehydrogenase 3 subunit α in AFB1 induced liver lesion. Yang C, Fan J, Zhuang Z, et al. Toxicol. Lett. 224(3), 371-9, (2014)

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Photodegradation of non-ionic surfactant with different ethoxy groups in aqueous effluents by the photo-Fenton process. da Silva SS, Chiavone-Filho O, Neto EL, et al. Environ. Technol. 35(9-12), 1556-64, (2014)

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Tooth bleaching induces changes in the vascular permeability of rat incisor pulps. Ferreira VG, Nabeshima CK, Marques MM, et al. Am. J. Dent. 26(5), 298-300, (2013)

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Microwave-enhanced Fenton-like system, Cu(II)/H2O2, for olive mill wastewater treatment. Iboukhoulef H, Amrane A, and Kadi H Environ. Technol. 34(5-8), 853-60, (2013)

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Anti-apoptotic roles for the mutant p53R248Q through suppression of p53-regulated apoptosis-inducing protein 1 in the RA-derived fibroblast-like synoviocyte cell line MH7A. Igarashi H, Hirano H, Yahagi A, et al. Clin. Immunol. 150(1), 12-21, (2014)

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Effects of hyperbaric oxygen treatment on antimicrobial function and apoptosis of differentiated HL-60 (neutrophil-like) cells. Almzaiel AJ, Billington R, Smerdon G, et al. Life Sci. 93(2-3), 125-31, (2013)

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An electrochemical H2O2 detection method based on direct electrochemistry of myoglobin immobilized on gold deposited ITO electrode. Dengale SM, Yagati AK, Chung YH, et al. J. Nanosci. Nanotechnol. 13(9), 6424-8, (2013)

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Protective roles of nitric oxide on seed germination and seedling growth of rice (Oryza sativa L.) under cadmium stress. He J, Ren Y, Chen X, et al. Ecotoxicol. Environ. Saf. 108, 114-9, (2014)

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Oxidative stress response induced by atrazine in Palaemonetes argentinus: the protective effect of vitamin E. Griboff J, Morales D, Bertrand L, et al. Ecotoxicol. Environ. Saf. 108, 1-8, (2014)

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Differential expression and anti-oxidant function of glutathione peroxidase 3 in mouse uterus during decidualization. Xu X, Leng JY, Gao F, et al. FEBS Lett. 588(9), 1580-9, (2014)

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In vitro effect of multiple hydrogen peroxide gas plasma sterilizations on the rate of closure of ameroid constrictors. Thompson EM, Towle Millard HA, Moore GE, et al. Am. J. Vet. Res. 75(10), 924-8, (2014)

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The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Kim DE, Kim B, Shin HS, et al. Exp. Cell Res. 327(2), 264-75, (2014)

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Roles of mitochondrial fragmentation and reactive oxygen species in mitochondrial dysfunction and myocardial insulin resistance. Watanabe T, Saotome M, Nobuhara M, et al. Exp. Cell Res. 323(2), 314-25, (2014)

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Airborne bacterial reduction by spraying slightly acidic electrolyzed water in a laying-hen house. Zheng W, Kang R, Wang H, et al. J. Air Waste Manag. Assoc. 63(10), 1205-11, (2013)

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Ordered cleavage of myeloperoxidase ester bonds releases active site heme leading to inactivation of myeloperoxidase by benzoic acid hydrazide analogs. Huang J, Smith F, and Panizzi P Arch. Biochem. Biophys. 548, 74-85, (2014)

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Biological and immunological characterization of recombinant Yellow Fever 17D viruses expressing a Trypanosoma cruzi Amastigote Surface Protein-2 CD8+ T cell epitope at two distinct regions of the genome. Nogueira RT Virol. J. 8, 127, (2011)

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Electron paramagnetic resonance and electron-nuclear double resonance studies of the reactions of cryogenerated hydroperoxoferric-hemoprotein intermediates. Davydov R, Laryukhin M, Ledbetter-Rogers A, et al. Biochemistry 53(30), 4894-903, (2014)

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Effects of quercetin on hemoglobin-dependent redox reactions: relationship to iron-overload rat liver injury. Lu NH, Chen C, He YJ, et al. J. Asian Nat. Prod. Res. 15(12), 1265-76, (2013)

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Antiaging, antistress and ROS scavenging activity of crude extract of Ocimum sanctum (L.) in Caenorhabditis elegans (Maupas, 1900). Pandey R, Gupta S, Shukla V, et al. Indian J. Exp. Biol. 51(7), 515-21, (2013)

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Analysis of the expression and antioxidant activity of 2-Cys peroxiredoxin protein in Fasciola gigantica. Sangpairoj K, Changklungmoa N, Vanichviriyakit R, et al. Exp. Parasitol. 140, 24-32, (2014)

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Neuroprotective effects of corn silk maysin via inhibition of H2O2-induced apoptotic cell death in SK-N-MC cells. Choi DJ, Kim SL, Choi JW, et al. Life Sci. 109(1), 57-64, (2014)

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Cinnamon polyphenols attenuate the hydrogen peroxide-induced down regulation of S100β secretion by regulating sirtuin 1 in C6 rat glioma cells. Qin B, Panickar KS, and Anderson RA Life Sci. 102(1), 72-9, (2014)

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Disturbance of redox homeostasis by ornithine and homocitrulline in rat cerebellum: a possible mechanism of cerebellar dysfunction in HHH syndrome. Zanatta A, Viegas CM, Tonin AM, et al. Life Sci. 93(4), 161-8, (2013)

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In vitro enzyme-mimic activity and in vivo therapeutic potential of HSJ-0017, a novel Mn porphyrin-based antioxidant enzyme mimic. Li BQ, Dong X, Li N, et al. Exp. Biol. Med. (Maywood.) 239(10), 1366-79, (2014)

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LX loaded nanoliposomes synthesis, characterization and cellular uptake studies in H2O2 stressed SH-SY5Y cells. Hasan M, Iqbal J, Awan U, et al. J. Nanosci. Nanotechnol. 14(6), 4066-71, (2014)

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Electrocatalytic activity of silver nanoparticles modified glassy carbon electrode as amperometric sensor for hydrogen peroxide. Majil SK, Dutta AK, Srivastava DN, et al. J. Nanosci. Nanotechnol. 13(7), 4969-74, (2013)

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Physicochemical and biofunctional properties of crab chitosan nanoparticles. Nguyen TH, Kwak HS, and Kim SM J. Nanosci. Nanotechnol. 13(8), 5296-304, (2013)

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Slightly acidic electrolyzed water for reducing airborne microorganisms in a layer breeding house. Hao X, Cao W, Li B, et al. J. Air Waste Manag. Assoc. 64(4), 494-500, (2014)

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Induction of miR-21-PDCD4 signaling by tungsten carbide-cobalt nanoparticles in JB6 cells involves ROS-mediated MAPK pathways. Hou L, Bowman L, Meighan TG, et al. J. Environ. Pathol. Toxicol. Oncol. 32(1), 41-51, (2013)

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Prostacyclin and thromboxane A2 levels in children and adolescents with an inherited predisposition to coronary heart disease: a family study. Akimova EV Coron. Artery Dis. 5(9), 761-5, (1994)

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MiR-124 protects human hepatic L02 cells from H2O2-induced apoptosis by targeting Rab38 gene. Li X, Yi S, Deng Y, et al. Biochem. Biophys. Res. Commun. 450(1), 148-53, (2014)

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WISP 1 is an important survival factor in human mesenchymal stromal cells. Schlegelmilch K, Keller A, Zehe V, et al. Gene 551(2), 243-54, (2014)

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Membrane-integrated hybrid system for the effective treatment of ammoniacal wastewater of coke-making plant: a volume reduction approach. Kumar R and Pal P Environ. Technol. 35(13-16), 2018-27, (2014)

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Degradation of sulphamethazine by means of an improved photo-Fenton process involving a hydrogen peroxide systematic dosage. Yamal-Turbay E, González LP, Graells M, et al. Environ. Technol. 35(13-16), 1695-701, (2014)

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Effects of activated carbon fibre-supported metal oxide characteristics on toluene removal. Liu ZS, Peng YH, and Li WK Environ. Technol. 35(9-12), 1499-507, (2014)

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Pretreatment of old-age landfill leachate by microwave-assisted catalytic oxidation in the presence of activated carbon. Xu XC, Zhang HT, Dong ZY, et al. Environ. Technol. 34(17-20), 2853-8, (2013)

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Low toxic effects of a whitening strip to cultured pulp cells. Soares DG, Pontes EC, Ribeiro AP, et al. Am. J. Dent. 26(5), 283-5, (2013)

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Post-treatment of coking industry wastewater by the electro-Fenton process. Güçlü D, Sahinkaya S, and Sirin N Water Environ. Res. 85(5), 391-6, (2013)

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Preoperative hydroperoxide concentrations are associated with a risk of postoperative complications after cardiac surgery. Suehiro K, Tanaka K, Matsuura T, et al. Anaesth. Intensive Care 42(4), 487-94, (2014)

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Calcium/calmodulin-dependent kinases are involved in growth, thermotolerance, oxidative stress survival, and fertility in Neurospora crassa. Kumar R and Tamuli R Arch. Microbiol. 196(4), 295-305, (2014)

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Required characteristics of Paenibacillus polymyxa JB-0501 as potential probiotic. Naghmouchi K, Baah J, Cudennec B, et al. Arch. Microbiol. 195(8), 537-43, (2013)

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Antihemolytic activity and mineral contents of Juglans regia L. flowers. Ebrahimzadeh MA, Nabavi SF, and Nabavi SM Eur. Rev. Med. Pharmacol. Sci. 17(14), 1881-3, (2013)

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Genetic ablation of plasmoDJ1, a multi-activity enzyme, attenuates parasite virulence and reduces oocyst production. Singhal N, Atul, Mastan BS, et al. Biochem. J. 461(2), 189-203, (2014)

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Introduction of a degassing membrane technology into anaerobic wastewater treatment. Bandara WM, Ikeda M, Satoh H, et al. Water Environ. Res. 85(5), 387-90, (2013)

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Merck 14,4798

Fieser 1,457 / Fieser 2,216 / Fieser 3,154 / Fieser 4,253 / Fieser 5,337 / Fieser 6,286 / Fieser 7,174 / Fieser 8,247 / Fieser 9,241 / Fieser 10,201 / Fieser 12,242 / Fieser 13,145 / Fieser 14,176 / Fieser 15,166 / Fieser 16,177 / Fieser 17,146

Corp MSDS 1 (1), 1898:B / RegBook 1 (3), 3293:C / Sax 6, 1550

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