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H113 Sigma

2-Hydroxysaclofen

solid

Synonym: 3-Amino-2-(4-chlorophenyl)-2-hydroxypropanesulfonic acid

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Properties

Related Categories A - H, Amino Acids, Biochemicals and Reagents, Modified Amino Acids
InChI Key   WBSMZVIMANOCNX-UHFFFAOYSA-N
form   solid
mp   267-269 °C
solubility   H2O: soluble1 mg/mL
  0.1 M HCl: soluble1.2 mg/mL
  methanol: soluble1.4 mg/mL
  DMSO: soluble28 mg/mL
  0.1 M NaOH: soluble9.5 mg/mL
storage temp.   2-8°C

Description

Biochem/physiol Actions

GABAB receptor antagonist which shows higher selectivity for the GABAB receptor than does phaclofen.

Potent and selective antagonist at GABAB receptors.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. H113.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

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Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1759 8 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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