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H2779 Sigma

HistoChoice® Clearing Agent Green Alternative



Related Categories 12 Principles Aligned Products, Chemical Synthesis, Greener Alternative Products, Life Sciences
form   liquid
greener alternative product characteristics   Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.
storage temp.   room temp


Frequently Asked Questions

Frequently Asked Questions are available for this Product.

General description

HistoChoice® is a patented, complex mixture of agents that allow tissues to retain their structure, antigenic sites and nucleic acid sites. This formulation in non-citrus, contains no mercury, formaldehyde or glutaraldehyde.

Sigma Life Science is committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing.


HistoChoice® Clearing Agent is suitable as an alternative to toluene and xylene for dewaxing paraffin tissue sections. Prepared slides are suitable for antibody probing applications and in situ hybridizations.

Features and Benefits

• Non-toxic and odorless
• Preserves native antigenic and nucleic acid sites
• Tissues retain original structure

Legal Information

HistoChoice is a registered trademark of Amresco, Inc.

Price and Availability

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
NA 1993 / PGIII
WGK Germany 
Flash Point(F) 
141.8 °F
Flash Point(C) 
61 °C


Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
Is HistoChoice Clearing Agent, product H2779, compatible with polycarbonate?
The supplier of HistoChoice Clearing Agent has reported no incompatibilities were observed when polycarbonate was exposed to HistoChoice Clearning Agent for at least 1 hour.
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Protocols & Articles

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Greener Alternatives Three Categories

A new icon has been added to identify our Greener alternative products. Products with this icon fulfill one of the three criteria.
Keywords: Alternative energy, Ceramics, Environmental, Green chemistry, Materials Science, Nanomaterials, PAGE

Peer-Reviewed Papers


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