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H3261 Sigma

2-Mercaptopyridine N-oxide sodium salt

≥96%

Synonym: 1-Hydroxy-2-pyridinethione sodium salt, 2-Mercaptopyridine-1-oxide sodium salt, 2-Pyridinethiol-1-oxide sodium salt, Pyrithione sodium salt

  • CAS Number 3811-73-2

  • Empirical Formula (Hill Notation) C5H4NNaOS

  • Molecular Weight 149.15

  •  Beilstein Registry Number 4026050

  •  EC Number 223-296-5

  •  MDL number MFCD01941547

  •  PubChem Substance ID 24895565

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics G-M, Antifungal, Biochemicals and Reagents,
biological source   from synthetic
InChI Key   WNGMMIYXPIAYOB-UHFFFAOYSA-M
assay   ≥96%
color   faintly beige
  white to light yellow
solubility   H2O: 50 mg/mL
Mode of action   cell membrane | interferes
antibiotic activity spectrum   fungi

Description

Biochem/physiol Actions

2-Mercaptopyridine N-oxide is a zinc ionophore that transports zinc into cells.

Application

2-Mercaptopyridine N-oxide can be used to generate bidentate oxothiolane chelates with transition metals.

2-Mercaptopyridine N-oxide, also called pyrithione, is added to cells in culture so metals enter them readily without relying on transporters. It is used to study picornavirus infections.

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
UT9000000
Protocols & Articles
Peer-Reviewed Papers
15

References

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