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H3656 Sigma

trans-4-Hydroxy-L-proline

microbial, cell culture tested

Synonym: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, Hyp

  • CAS Number 51-35-4

  • Empirical Formula (Hill Notation) C5H9NO3

  • Molecular Weight 131.13

  •  Beilstein Registry Number 81441

  •  EC Number 200-091-9

  •  MDL number MFCD00064320

  •  PubChem Substance ID 329815200

  • Popular Documents:  FTIR (PDF)  

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Properties

Related Categories A - H, Amino Acids, Biochemicals and Reagents, Modified Amino Acids
biological source   microbial
InChI Key   PMMYEEVYMWASQN-DMTCNVIQSA-N
assay   ≥98% (TLC)
mp   273 °C (dec.)(lit.)
suitability   cell culture tested

Description

Other Notes

Natural constituent of animal structural proteins such as collagen and elastin.

Biochem/physiol Actions

Trans-4-Hydroxy-L-proline is a chiral compound used in the synthesis of depsilairdin analogues; hydroxymethyl-2-pyrrolidinone (5) nucleoside analogs; enantiomerically pure polyheterocyclic spiro-β-lactams and the ABC-ring system of the antitumor antibiotic MPC1001.

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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H5534 trans-4-Hydroxy-L-proline, BioReagent, suitable for cell culture, ≥98.5%

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