|Related Categories||Amino Acid Derivatives, Amino Acids, Biochemicals and Reagents, Chemical Biology, Chemical Synthesis,|
|solubility||1 M HCl: soluble|
|Gene Information||human ... CA1(759), CA2(760)|
5, 25 g in poly bottle
D-Histidine may be used in the design of peptide drugs, cationic peptides, such as analogues of carnosine. D-Histidine may also be used as a heavy metal sequestration agent.
Design, synthesis, and evaluation of carnosine derivatives as selective and efficient sequestering agents of cytotoxic reactive carbonyl species. Vistoli G, Orioli M, Pedretti A, et al. ChemMedChem 4, 967-975, (2009)
Design, synthesis, ADME properties, and pharmacological activities of β-alanyl-D-histidine(D-carnosine) prodrugs with improved bioavailability. Orioli M, Vistoli G, Regazzoni L, et al. ChemMedChem 6, 1269-1282, (2011)
Carbonic anhydrase activators: Activation of the human cytosolic isozyme III and membrane-associated isoform IV with amino acids and amines. Daniela Vullo et al Bioorg. Med. Chem. Lett. 18, 4303-7, (2008)
Carbonic anhydrase activators: activation of the archaeal beta-class (Cab) and gamma-class (Cam) carbonic anhydrases with amino acids and amines. Alessio Innocenti et al Bioorg. Med. Chem. Lett. 18, 6194-8, (2008)
Carbonic anhydrase activators: activation of the beta-carbonic anhydrase Nce103 from the yeast Saccharomyces cerevisiae with amines and amino acids. Semra Isik et al Bioorg. Med. Chem. Lett. 19, 1662-5, (2009)
Carbonic anhydrase activators: Activation of the beta-carbonic anhydrase from the pathogenic yeast Candida glabrata with amines and amino acids. Alessio Innocenti et al Bioorg. Med. Chem. Lett. 20, 1701-4, (2010)
Carbonic anhydrase activators: activation of the beta-carbonic anhydrases from the pathogenic fungi Candida albicans and Cryptococcus neoformans with amines and amino acids. Alessio Innocenti et al Bioorg. Med. Chem. 18, 1034-7, (2010)
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