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H4002 Sigma

DL-3-Hydroxynorvaline

≥98% (TLC)

Synonym: α-Amino-β-hydroxyvaleric acid, 2-Amino-3-hydroxypentanoic acid, 3-Hydroxy-2-aminopentanoic acid, DL-β-Hydroxynorvaline, HNV

  • CAS Number 2280-42-4

  • Empirical Formula (Hill Notation) C5H11NO3

  • Molecular Weight 133.15

  •  Beilstein Registry Number 1722350

  •  MDL number MFCD00010516

  •  PubChem Substance ID 24895609

  •  eCl@ss 32160406

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Properties

Related Categories A - H, Amino Acids, Biochemicals and Reagents, Modified Amino Acids
InChI Key   LGVJIYCMHMKTPB-UHFFFAOYSA-N
assay   ≥98% (TLC)
storage temp.   −20°C

Description

Packaging

1 g in poly bottle

250 mg in poly bottle

Biochem/physiol Actions

3-Hydroxynorvaline (HNV) is a microbial, α amino acid threonine analogue which has antiviral activity (herpes virus) and is toxic to mammalian cells (embryotoxic and teratogenic) presumably via incorporation into proteins. 3-Hydroxynorvaline may be used as an unnatural amino acid to study the fidelity of protein translation at the level of acyl-tRNA editing. 3-Hydroxynorvaline may also be used to study enzymes and molecules involved in threonine metabolism.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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